Abdominal Imaging

, Volume 34, Issue 2, pp 211–216

Dilated cisternae chyli: a sign of uncompensated cirrhosis at MR imaging

  • Sachit K. Verma
  • Donald G. Mitchell
  • Diane Bergin
  • Yulia Lakhman
  • Amy Austin
  • Manisha Verma
  • David Assis
  • Stevene K. Herrine
  • Laurence Parker
Article

DOI: 10.1007/s00261-008-9369-7

Cite this article as:
Verma, S.K., Mitchell, D.G., Bergin, D. et al. Abdom Imaging (2009) 34: 211. doi:10.1007/s00261-008-9369-7

Abstract

Background

In order to retrospectively determine the frequency of dilated cisterna chyli (CC) on MR images in patients with cirrhosis, and to assess its value as a simple diagnostic imaging sign of uncompensated cirrhosis.

Methods

Study population included 257 patients (149 with pathologically proved cirrhosis and 108 control subjects without the history of chronic liver diseases) who had 1.5 T MR imaging. Cirrhosis patients were divided into compensated and uncompensated groups. Three independent observers qualitatively evaluated the visibility of CC 2 mm or greater in transverse diameter, identified as a tubular structure with fluid signal intensity. CC diameters greater than 6 mm were defined as dilated. Statistical analysis was performed by Student t-test and interobserver agreement via intraclass correlation coefficient.

Results

CCs with diameter 2 mm or more were recorded in 113 of 149 (76%) cirrhotic patients and 15 of 108 (14%) control subjects (P < 0.001). Dilated CCs were significantly more frequent in uncompensated than compensated cirrhotic patients (54% vs 5%, P < 0.001). The sensitivity, specificity, accuracy, and positive predictive value of dilated CC for uncompensated cirrhosis were 54%, 98%, 80%, and 96%, respectively.

Conclusions

Dilated CC can be used as a simple and specific sign complimentary to other findings of uncompensated cirrhosis.

Keywords

CirrhosisCisterna chyliDilatedLymphMRI

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Sachit K. Verma
    • 1
  • Donald G. Mitchell
    • 1
  • Diane Bergin
    • 1
  • Yulia Lakhman
    • 1
  • Amy Austin
    • 1
  • Manisha Verma
    • 2
  • David Assis
    • 2
  • Stevene K. Herrine
    • 2
  • Laurence Parker
    • 1
  1. 1.Department of RadiologyThomas Jefferson University HospitalPhiladelphiaUSA
  2. 2.Department of MedicineThomas Jefferson University HospitalPhiladelphiaUSA