Original article

Abdominal Imaging

, Volume 29, Issue 2, pp 228-230

Fatal, complete splenic infarction and hepatic infection due to disseminated Trichosporon beigelii infection

  • S. G. ViscomiAffiliated withDivision of Abdominal Imaging and Intervention, Department of Radiology, Brigham & Women’s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115
  • , K. J. MorteléAffiliated withDivision of Abdominal Imaging and Intervention, Department of Radiology, Brigham & Women’s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115 Email author 
  • , V. CantisaniAffiliated withDivision of Abdominal Imaging and Intervention, Department of Radiology, Brigham & Women’s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115
  • , J. GlickmanAffiliated withDepartment of Pathology, Brigham & Women’s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115
  • , S. G. SilvermanAffiliated withDivision of Abdominal Imaging and Intervention, Department of Radiology, Brigham & Women’s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115

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Abstract

We report on a 56-year-old woman with acute lymphocytic leukemia who presented with right upper quadrant pain, fever, nausea, and vomiting. Laboratory studies confirmed fungemia with Trichosporum beigelii, and contrast-enhanced computed tomography of the abdomen demonstrated numerous low-attenuation liver lesions and a hypodense spleen with capsular enhancement suggestive of complete splenic infarction. Subsequent splenectomy confirmed that the spleen was completely infarcted and infiltrated with Trichosporum. The patient had a difficult postoperative course and died despite aggressive antifungal therapy.

Keywords

Computed tomography—Spleen infection—Spleen infarction—Trichosporum beigelii