European Journal of Nuclear Medicine and Molecular Imaging

, Volume 37, Issue 4, pp 842-848

First online:

Open Access This content is freely available online to anyone, anywhere at any time.

Guidelines for the labelling of leucocytes with 99mTc-HMPAO

  • Erik F. J. de VriesAffiliated withDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen
  • , Manel RocaAffiliated withRadiopharmacy Unit, Nuclear Medicine Department, Hospital Universitario de Bellvitge
  • , Francois JamarAffiliated withNuclear Medicine, Université Catholique de Louvain
  • , Ora IsraelAffiliated withDepartments of Nuclear Medicine, Rambam Health Care Campus
  • , Alberto SignoreAffiliated withNuclear Medicine Unit, 2nd Faculty of Medicine, University “Sapienza”Medicina Nucleare, Ospedale S. Andrea, University of Rome “Sapienza” Email author 


We describe here a protocol for labelling autologous white blood cells with 99mTc-HMPAO based on previously published consensus papers and guidelines. This protocol includes quality control and safety procedures and is in accordance with current European Union regulations and International Atomic Energy Agency recommendations.


Guidelines White blood cells Scintigraphy 99mTc-HMPAO Infection