Skip to main content

Advertisement

SpringerLink
Log in

Inverted verrucous carcinoma of the buttock mimicking abscess and gossypiboma: MR and pathologic correlation

  • Case Report
  • Published:
Skeletal Radiology Aims and scope Submit manuscript

Abstract

Verrucous carcinoma (VC) is an uncommon, low-grade variant of squamous cell carcinoma. Its benign histologic appearance and indolent course may lead to a delayed diagnosis. We report a rare case of an inverted verrucous carcinoma of the buttock presenting as a slow-growing subcutaneous lesion with a draining sinus and no exophytic component, clinically mimicking abscess and gossypiboma, with magnetic resonance imaging (MRI) and pathologic correlation. Biopsy of the lesional base is mandatory for accurate diagnosis. An enhancement pattern with a convoluted undulating appearance in a subcutaneous lesion displayed on MRI should raise a consideration of inverted VC in the differential diagnosis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4

References

  1. Cruickshank AH, McConnell EM, Miller DG. Malignancy in scars, chronic ulcers, and sinuses. J Clin Pathol. 1963;16:573–80.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  2. Smith J, Mello LF, Nogueira Neto NC, Meohas W, Pinto LW, Campos VA, et al. Malignancy in chronic ulcers and scars of the leg (Marjolin’s ulcer): a study of 21 patients. Skelet Radiol. 2001;30(6):331–7.

    Article  CAS  Google Scholar 

  3. Meaume S, Fromantin I, Teot L. Neoplastic wounds and degenerescence. J Tissue Viability. 2013;22(4):122–30.

    Article  CAS  PubMed  Google Scholar 

  4. Kraus FT, Perezmesa C. Verrucous carcinoma. Clinical and pathologic study of 105 cases involving oral cavity, larynx and genitalia. Cancer. 1966;19(1):26–38.

    Article  CAS  PubMed  Google Scholar 

  5. Becker M, Moulin G, Kurt AM, Zbären P, Dulgerov P, Marchal F, et al. Atypical squamous cell carcinoma of the larynx and hypopharynx: radiologic features and pathologic correlation. Eur Radiol. 1998;8(9):1541–51.

    Article  CAS  PubMed  Google Scholar 

  6. Ferlito A, Recher G. Ackerman’s tumor (verrucous carcinoma) of the larynx: a clinicopathologic study of 77 cases. Cancer. 1980;46(7):1617–30.

    Article  CAS  PubMed  Google Scholar 

  7. Ackerman LV. Verrucous carcinoma of the oral cavity. Surgery. 1948;23(4):670–8.

    CAS  PubMed  Google Scholar 

  8. Aird I, Johnson HD, Lennox B, et al. Epithelioma cuniculatum, a variety of squamous carcinoma peculiar to the foot. Br J Surg. 1954;42:245–50.

    Article  CAS  PubMed  Google Scholar 

  9. Anscombe AM, Isaacson P. An unusual variant of squamous cell carcinoma (inverted verrucous carcinoma) arising in a pilonidal sinus. Histopathology. 1983;7(1):123–7.

    Article  CAS  PubMed  Google Scholar 

  10. Theodorou SJ, Theodorou DJ, Bona SJ, Farooki S. Primary squamous cell carcinoma: an incidental toe mass. AJR Am J Roentgenol. 2005;184(3 Suppl):S110–1.

    Article  PubMed  Google Scholar 

  11. Barnhill RL. Tumors of the epidermis. In: Barnhill RL, editor. Textbook of dermatopathology. New York: McGraw Hill; 1998. p. 521–5.

    Google Scholar 

  12. Arefi M, Philipone E, Caprioli R, Haight J, Richardson H, Sheng C. A case of verrucous carcinoma (epithelioma cuniculatum) of the heel mimicking infected epidermal cyst and gout. Foot Ankle Spec. 2008;1(5):297–9.

    Article  PubMed  Google Scholar 

  13. Melo CR, Melo IS. Carcinoma cuniculatum of the buttock. An unusual case with an inverted growth. Dermatologica. 1989;179(1):38–41.

    Article  CAS  PubMed  Google Scholar 

  14. Yip KM, Lin-Yip J, Kumta S, Leung PC. Subcutaneous (“inverted”) verrucous carcinoma with bone invasion. Am J Dermatopathol. 1997;19(1):83–6.

    Article  CAS  PubMed  Google Scholar 

  15. Kao GF, Graham JH, Helwig EB. Carcinoma cuniculatum (verrucous carcinoma of the skin): a clinicopathologic study of 46 cases with ultrastructural observations. Cancer. 1982;49(11):2395–403.

    Article  CAS  PubMed  Google Scholar 

  16. Wasserman PL, Taylor RC, Pinillia J, Wuertzer SD. Verrucous carcinoma of the foot and enhancement assessment by MRI. Skelet Radiol. 2009;38(4):393–5.

    Article  Google Scholar 

  17. García-Gavín J, González-Vilas D, Rodríguez-Pazos L, Sánchez-Aguilar D, Toribio J. Verrucous carcinoma of the foot affecting the bone: utility of the computed tomography scanner. Dermatol Online J. 2010;16(2):8.

    PubMed  Google Scholar 

  18. Mirigliano E, LaTour R, Abramczuk JW. Squamous cell carcinoma of the foot mimicking osteomyelitis: a case report. J Foot Ankle Surg. 2011;50(4):480–5.

    Article  PubMed  Google Scholar 

  19. Dogan G, Oram Y, Hazneci E, Ozen S, Karincaoğlu Y, Ciralik H. Three cases of verrucous carcinoma. Australas J Dermatol. 1998;39(4):251–4.

    Article  CAS  PubMed  Google Scholar 

  20. Bhushan M, Ferguson JE, Hutchinson CE, Muston HL. Carcinoma cuniculatum of the foot assessed by magnetic resonance scanning. Clin Exp Dermatol. 2001;26(5):419–22.

    Article  CAS  PubMed  Google Scholar 

  21. Peng HH, Wang TH, Huang KG, Ng KK, Hsueh S, Chen MY. Combined ultrasound and magnetic resonance imaging findings on cervical verrucous carcinoma with endometrial invasion: a case report. J Reprod Med. 2007;52(5):441–4.

    PubMed  Google Scholar 

  22. Wolf H, Platzer P, Vécsei V. Verrucous carcinoma of the tibia arising after chronic osteomyelitis: a case report. Wien Klin Wochenschr. 2009;121(1–2):53–6.

    Article  PubMed  Google Scholar 

  23. Kominami M, Fujikawa A, Tamura T, Naoi Y, Horikawa O. Retained surgical sponge in the thigh: report of the third known case in the limb. Radiat Med. 2003;21(5):220–2.

    PubMed  Google Scholar 

  24. Kim CK, Park BK, Ha H. Gossypiboma in abdomen and pelvis: MRI findings in four patients. AJR. 2007;189:814–7.

    Article  PubMed  Google Scholar 

  25. Sugimura H, Tamura S, Kakitsubata Y, Kakitsubata S, Uwada O, Kihara Y, et al. Magnetic resonance imaging of retained surgical sponges. Case report. Clin Imaging. 1992;16(4):259–62.

    Article  CAS  PubMed  Google Scholar 

  26. Puri A, Anchan C, Jambhekar NA, Agarwal MG, Badwe RA. Recurrent gossypiboma in the thigh. Skelet Radiol. 2007;36 Suppl 1:S95–100.

    Article  Google Scholar 

  27. Lo CP, Hsu CC, Chang TH. Gossypiboma of the leg: MR imaging characteristics. A Case Report. Korean J Radiol. 2003;4(3):191–3.

    Article  PubMed Central  PubMed  Google Scholar 

  28. Kim HS, Chung TS, Suh SH, et al. MR imaging findings of paravertebral gossypiboma. AJNR. 2007;28:709–13.

    CAS  PubMed  Google Scholar 

  29. Okten AI, Mehmet A, Gezercan Y. Textiloma: a case of foreign body mimicking a spinal mass. Eur Spine J. 2006;15:626–9.

    Article  PubMed Central  PubMed  Google Scholar 

  30. Manzella A, Filho PB, Albuquerque E, Farias F, Kaercher J. Imaging of gossypibomas: pictorial review. AJR Am J Roentgenol. 2009;193(6 Suppl):S94–101.

    Article  PubMed  Google Scholar 

  31. Abdul-Karim FW, Benevenia J, Pathria MN, Makley JT. Case report 736: retained surgical sponge (gossypiboma) with a foreign body reaction and remote and organizing hematoma. Skelet Radiol. 1992;21(7):466–9.

    Article  CAS  Google Scholar 

  32. Sawhney S, Jain R, Kakaria A, Chopra P. Marjolin’s Ulcer: radiographic and magnetic resonance appearances in two cases. Sultan Qaboos Univ Med J. 2009;9(2):162–6.

    PubMed Central  PubMed  Google Scholar 

  33. Koch H, Kowatsch E, Hödl S, Smola MG, Radl R, Hofmann T, et al. Verrucous carcinoma of the skin: long-term follow-up results following surgical therapy. Dermatol Surg. 2004;30(8):1124–30.

    PubMed  Google Scholar 

Download references

Conflict of interest

The authors declare that they have no conflict of interest.

Author information

Authors and Affiliations

  1. Department of Radiology, Einstein Medical Center Philadelphia, 5501 Old York Road, Philadelphia, PA, 19141, USA

    Bing Hu, Tetyana Gorbachova & Shuchi K. Rodgers

  2. Department of Pathology, Einstein Medical Center Montgomery, East Norriton, PA, USA

    Paul Belser

  3. Department of Surgery, Einstein Medical Center Montgomery, East Norriton, PA, USA

    Robert Schiowitz

Authors
  1. Bing Hu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Tetyana Gorbachova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Paul Belser
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Shuchi K. Rodgers
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Robert Schiowitz
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Tetyana Gorbachova.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Hu, B., Gorbachova, T., Belser, P. et al. Inverted verrucous carcinoma of the buttock mimicking abscess and gossypiboma: MR and pathologic correlation. Skeletal Radiol 44, 1371–1375 (2015). https://doi.org/10.1007/s00256-015-2163-z

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00256-015-2163-z

Keywords

Search

Navigation