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Case report: imaging features in a renal transplant patient with calcineurin inhibitor-induced pain syndrome (CIPS)

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Abstract

Post-transplant distal limb bone marrow edema syndrome or calcineurin inhibitor-induced pain syndrome (CIPS) is generally a self-limiting but debilitating acute pain syndrome that has been reported in 2–14 % of renal transplant recipients. The disease is extensively described in the transplant literature in patients receiving the calcineurin inhibitors cyclosporine and tacrolimus. We present a case of CIPS arising in a patient 73 days after renal allograft, review the imaging findings, and discuss proposed etiologies and differential diagnoses. To the authors’ knowledge, CIPS has not been characterized as a distinct entity in the radiology literature.

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The authors declare that they have no conflicts of interest.

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Correspondence to Russell W. Chapin.

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Chapin, R.W., Chua, E., Simmons, J. et al. Case report: imaging features in a renal transplant patient with calcineurin inhibitor-induced pain syndrome (CIPS). Skeletal Radiol 42, 1311–1315 (2013). https://doi.org/10.1007/s00256-013-1616-5

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  • DOI: https://doi.org/10.1007/s00256-013-1616-5

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