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Complete Repair of Tetralogy of Fallot in the Neonatal Versus Non-neonatal Period: A Meta-analysis

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Abstract

It is unclear if neonatal tetralogy of Fallot repair offers better outcomes compared to repair later in infancy. We therefore conducted a meta-analysis comparing outcomes of neonatal and non-neonatal repair. Manuscripts were identified and reviewed for quality and bias with favorably scored manuscripts being included in the final meta-analysis. Several perioperative and postoperative variables were compared. A total of 8 studies with 3858 patients were included in the analysis. Of these patients, 19% underwent neonatal repair. Neonatal repair was associated with increased mortality, longer intensive care unit stays, and longer total hospital length of stay.

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Authors and Affiliations

  1. Division of Cardiology and Cardiothoracic Surgery, Children’s Hospital of Wisconsin/ Medical College of Wisconsin, 9000 Wisconsin Avenue, Milwaukee, WI, 53226, USA

    Rohit S. Loomba, Matthew W. Buelow & Ronald K. Woods

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  1. Rohit S. Loomba
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  2. Matthew W. Buelow
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  3. Ronald K. Woods
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Correspondence to Rohit S. Loomba.

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Loomba, R.S., Buelow, M.W. & Woods, R.K. Complete Repair of Tetralogy of Fallot in the Neonatal Versus Non-neonatal Period: A Meta-analysis. Pediatr Cardiol 38, 893–901 (2017). https://doi.org/10.1007/s00246-017-1579-8

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