Abstract
The aim of this study was to propose a simple practical diagnostic criterion for pre-hypertension (pre-HTN) and hypertension (HTN) in the pediatric age group. This study was conducted on a nationally representative sample of 14,880 students, aged 6–18 years. HTN and pre-HTN were defined as systolic blood pressure (SBP) and/or diastolic blood pressure (DBP) ≥ 95 and 90–95th percentile for age, gender, and height, respectively. By using the area under the curve (AUC) of the receiver operator characteristic curves, we estimated the diagnostic accuracy of two indexes of SBP-to-height ratio (SBPHR) and DBP-to-height (DBPHR) to define pre-HTN and HTN. Overall, SBPHR performed relatively well in classifying subjects to HTN (AUC 0.80–0.85) and pre-HTN (AUC 0.84–0.90). Likewise, DBPHR performed relatively well in classifying subjects to HTN (AUC 0.90–0.97) and pre-HTN (AUC 0.70–0.83). Two indexes of SBPHR and DBPHR are considered as valid, simple, inexpensive, and accurate tools to diagnose pre-HTN and HTN in pediatric age group.
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A comprehensive verbal description of the nature and purpose of the study was given to the students and their parents. Written informed consent was obtained from parents. Ethical committees of Tehran University of Medical Sciences and Isfahan University of Medical Sciences reviewed and approved study protocols.
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Mostafa Qorbani and Ramin Heshmat have contributed equally as corresponding authors.
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Kelishadi, R., Bahreynian, M., Heshmat, R. et al. Accuracy of Blood Pressure-to-Height Ratio to Define Elevated Blood Pressure in Children and Adolescents: The CASPIAN-IV Study. Pediatr Cardiol 37, 378–385 (2016). https://doi.org/10.1007/s00246-015-1287-1
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DOI: https://doi.org/10.1007/s00246-015-1287-1