Pediatric Cardiology

, Volume 31, Issue 2, pp 195–202

Parental Knowledge and Attitudes Toward Hypertrophic Cardiomyopathy Genetic Testing

  • Sara M. Fitzgerald-Butt
  • Lindsey Byrne
  • Cynthia A. Gerhardt
  • Kathryn Vannatta
  • Timothy M. Hoffman
  • Kim L. McBride
Original Article

DOI: 10.1007/s00246-009-9583-2

Cite this article as:
Fitzgerald-Butt, S.M., Byrne, L., Gerhardt, C.A. et al. Pediatr Cardiol (2010) 31: 195. doi:10.1007/s00246-009-9583-2

Abstract

Hypertrophic cardiomyopathy (HCM) is a common autosomal dominant condition with an increased risk of sudden cardiac death. Although clinical genetic testing can be used for confirmation of a clinical diagnosis as well as a predictive test, based on our clinical experience it is underutilized. Therefore, we developed and administered a questionnaire to assess potential determinants of parental interest in this testing. Of the 30 adult caregivers who participated, 80% had heard of genetic testing, whereas only 30% knew about genetic testing specifically for HCM. Once informed of the availability, 62% said they would consider testing in the future and 28% would consider it in the next year. Participants’ younger age, higher education level, knowledge of carrier testing, and positive view of genetic testing were significantly associated with the participant considering HCM genetic testing for their child (p ≤ 0.05). Based on a logistic regression model, age, education level, and knowing that HCM is an inherited disease were the best predictors of who would consider genetic testing. This study provides healthcare providers with a framework to understand caregivers’ knowledge and views of genetic testing, which can be used to improve clinical care for pediatric HCM patients.

Keywords

Hypertrophic cardiomyopathy Genetic screening Genetic counseling Pediatric Health knowledge attitudes practice 

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Sara M. Fitzgerald-Butt
    • 1
    • 3
  • Lindsey Byrne
    • 1
    • 5
  • Cynthia A. Gerhardt
    • 2
    • 3
  • Kathryn Vannatta
    • 2
    • 3
  • Timothy M. Hoffman
    • 3
    • 4
  • Kim L. McBride
    • 1
    • 3
  1. 1.Center for Molecular and Human GeneticsThe Research Institute at Nationwide Children’s HospitalColumbusUSA
  2. 2.Center for BioBehavioral HealthThe Research Institute at Nationwide Children’s HospitalColumbusUSA
  3. 3.Department of Pediatrics, College of MedicineThe Ohio State UniversityColumbusUSA
  4. 4.The Heart CenterNationwide Children’s HospitalColumbusUSA
  5. 5.Cancer GeneticsOhioHealthColumbusUSA

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