Neuroradiology

, Volume 52, Issue 1, pp 15–24

Neuroimaging after coma

Authors

  • Luaba Tshibanda
    • Coma Science Group, Cyclotron Research CenterUniversity and University Hospital of Liège
    • Department of NeuroradiologyUniversity Hospital of Liège
  • Audrey Vanhaudenhuyse
    • Coma Science Group, Cyclotron Research CenterUniversity and University Hospital of Liège
  • Mélanie Boly
    • Coma Science Group, Cyclotron Research CenterUniversity and University Hospital of Liège
    • Department of NeuroradiologyUniversity Hospital of Liège
    • Department of NeurologyUniversity Hospital of Liège
  • Andrea Soddu
    • Coma Science Group, Cyclotron Research CenterUniversity and University Hospital of Liège
  • Marie-Aurelie Bruno
    • Coma Science Group, Cyclotron Research CenterUniversity and University Hospital of Liège
  • Gustave Moonen
    • Department of NeurologyUniversity Hospital of Liège
    • Coma Science Group, Cyclotron Research CenterUniversity and University Hospital of Liège
    • Department of NeuroradiologyUniversity Hospital of Liège
    • Department of NeurologyUniversity Hospital of Liège
  • Quentin Noirhomme
    • Coma Science Group, Cyclotron Research CenterUniversity and University Hospital of Liège
Invited Review

DOI: 10.1007/s00234-009-0614-8

Cite this article as:
Tshibanda, L., Vanhaudenhuyse, A., Boly, M. et al. Neuroradiology (2010) 52: 15. doi:10.1007/s00234-009-0614-8

Abstract

Following coma, some patients will recover wakefulness without signs of consciousness (only showing reflex movements, i.e., the vegetative state) or may show non-reflex movements but remain without functional communication (i.e., the minimally conscious state). Currently, there remains a high rate of misdiagnosis of the vegetative state (Schnakers et. al. BMC Neurol, 9:35, 8) and the clinical and electrophysiological markers of outcome from the vegetative and minimally conscious states remain unsatisfactory. This should incite clinicians to use multimodal assessment to detect objective signs of consciousness and validate para-clinical prognostic markers in these challenging patients. This review will focus on advanced magnetic resonance imaging (MRI) techniques such as magnetic resonance spectroscopy, diffusion tensor imaging, and functional MRI (fMRI studies in both “activation” and “resting state” conditions) that were recently introduced in the assessment of patients with chronic disorders of consciousness.

Keywords

Vegetative stateDiffusion tensor imagingMR spectroscopyFunctional MRIConsciousness

Copyright information

© Springer-Verlag 2009