Experimental Brain Research

, Volume 164, Issue 3, pp 357–364

Localization of the human female breast in primary somatosensory cortex

  • Yvonne Rothemund
  • Michael Schaefer
  • Sabine M. Grüsser
  • Herta Flor
Research Article

DOI: 10.1007/s00221-005-2257-2

Cite this article as:
Rothemund, Y., Schaefer, M., Grüsser, S.M. et al. Exp Brain Res (2005) 164: 357. doi:10.1007/s00221-005-2257-2

Abstract

Rationale: Despite an extensive body of research on the topography of the primary somatosensory cortex (S1) little is known about the representation of the trunk. Aim: The aim of this study was to determine the representation of the breast in S1 in human females. Results: The representation of the human breast in primary somatosensory cortex was determined in ten healthy female subjects. Non-painful electrical stimulation of the mammilla (Th4 dermatome), groin (L1 dermatome) and the first digit of both sides of the body activated cutaneous receptors and thus elicited somatosensory evoked potentials. The representation of these body parts in primary somatosensory cortex (S1) was determined using neuroelectric source imaging. Equivalent current dipole localizations were overlaid with individual structural magnetic resonance images to account for individual cortical differences. The breast representation was localized between the representation of the groin and the first digit. In the medial–lateral direction the representation of the breast was approximately 15 mm lateral of the longitudinal fissure in the contralateral hemisphere. Source localizations were stable across subjects. However, one subject showed ipsilateral representation of the breast, which might be related to bilateral receptive fields of the ventral body midline representation. This study confirms the Penfield and Rasmussen (1950) invasive data by use of noninvasive source imaging.

Keywords

EEGTrunk representationElectrical stimulationSomatosensory evoked potential (SEP)Source localization

Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  • Yvonne Rothemund
    • 1
    • 4
    • 4
  • Michael Schaefer
    • 2
  • Sabine M. Grüsser
    • 3
  • Herta Flor
    • 1
  1. 1.Department of Clinical and Cognitive Neuroscience at the University of HeidelbergCentral Institute of Mental Health, J5MannheimGermany
  2. 2.Human Cortical Physiology Section NINDSNational Institutes of HealthBethesdaUSA
  3. 3.Institute for Medical PsychologyCenter for Humanities and Health SciencesBerlinGermany
  4. 4.University Hospital Charité Psychosomatic MedicineBerlinGermany