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Structure elucidation and immunological activity of a novel pectic polysaccharide from the stems of Avicennia marina

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Abstract

The structure of HAM-3-IIb-II, an acidic pectic polysaccharide in Avicennia marina, was characterized in detail and the immunological activity was investigated in this study. The results showed that HAM-3-IIb-II contained Rha, Ara, Gal, Glc, and GalA in a molar ratio of 1:2.8:2.4:6.1 and that HAM-3-IIb-II is a type I rhamnogalacturonan with branches of arabinose chains, galactosyl chains, and arabinogalactosyl chains. The backbone of HAM-3-IIb-II is mainly composed of disaccharide repeat units, →4)-α-d-GalA-(1 → 2)-α-l-Rhap-(1→. These repeats are predominantly linked to the O-4 of 1,2,4-linked α-l-Rhap in the branches of arabinose chains, galactosyl chains, and arabinogalactosyl chains. HAM-3-IIb-II had a significant effect on lipopolysaccharide-induced B lymphocyte proliferation, but it had little effect on concanavalin A-induced T lymphocyte proliferation compared with the control. This study provides a foundation for the exploration and utilization of A. marina in the future.

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Acknowledgments

This work was supported by the Natural Science Foundation of Zhejiang Province (LY12C20006).

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  1. School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan, 316000, China

    Xubo Fang & Xiaoe Chen

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  1. Xubo Fang
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  2. Xiaoe Chen
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Correspondence to Xiaoe Chen.

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Fang, X., Chen, X. Structure elucidation and immunological activity of a novel pectic polysaccharide from the stems of Avicennia marina . Eur Food Res Technol 236, 243–248 (2013). https://doi.org/10.1007/s00217-012-1877-6

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  • DOI: https://doi.org/10.1007/s00217-012-1877-6

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