European Food Research and Technology

, 227:1641

Influence of grape variety and their phenolic composition on vasorelaxing activity of young red wines

Authors

    • Departamento de Farmacología, Facultad de FarmaciaUniversidad Complutense de Madrid
  • Elena De La Hera
    • Departamento de Farmacología, Facultad de FarmaciaUniversidad Complutense de Madrid
  • M. Emilia Carretero
    • Departamento de Farmacología, Facultad de FarmaciaUniversidad Complutense de Madrid
  • Pilar Gómez-Serranillos
    • Departamento de Farmacología, Facultad de FarmaciaUniversidad Complutense de Madrid
  • M. Victoria Naval
    • Departamento de Farmacología, Facultad de FarmaciaUniversidad Complutense de Madrid
  • Angel M. Villar
    • Departamento de Farmacología, Facultad de FarmaciaUniversidad Complutense de Madrid
  • Marin Prodanov
    • Departamento de AgroalimentaciónInstituto Madrileño de Investigación y Desarrollo Rural
  • Visitación Vacas
    • Departamento de AgroalimentaciónInstituto Madrileño de Investigación y Desarrollo Rural
  • Teresa Arroyo
    • Departamento de AgroalimentaciónInstituto Madrileño de Investigación y Desarrollo Rural
  • Teresa Hernández
    • Instituto de Fermentaciones Industriales
  • Isabel Estrella
    • Instituto de Fermentaciones Industriales
Original Paper

DOI: 10.1007/s00217-008-0888-9

Cite this article as:
Ortega, T., De La Hera, E., Carretero, M.E. et al. Eur Food Res Technol (2008) 227: 1641. doi:10.1007/s00217-008-0888-9

Abstract

Red wine has been reported to exert beneficial effects in preventing cardiovascular diseases probably due to their polyphenols constituents. The vasorelaxant capacity and phenolic composition of four monovarietal young red wines Merlot, Tempranillo, Garnacha and Cabernet-Sauvignon obtained from grapes from 2004 vintage, cultivated under the same climatic and agricultural conditions, wine-making technology and storage conditions, were determined using vascular reactivity assay in rat aortic and high-performance liquid chromatography, respectively. Primary cultures of vascular smooth muscle cells from Wistar rats were also used to evaluate their survival prevention activity as well. Every studied wine present vasorelaxation effect, but the higher value corresponds to the analyzed Merlot wine, especially rich in phenolic compounds, mainly catechins and oligomeric proanthocyanidins and anthocyanin glycosides. This study further demonstrated previous investigations about the phenolic composition of wines relation with their vasorelaxation activity.

Keywords

Young monovarietal wineMerlotTempranilloGarnachaCabernet-SauvignonPhenolic compositionVasorelaxationVasoprotective

Copyright information

© Springer-Verlag 2008