Abstract
Transient osteoporosis of the hip (TOH) is a temporary clinical condition of unknown etiology which usually resolves with conservative therapy though may be complicated by fracture or progression to avascular necrosis (AVN). TOH may be slightly more prevalent in men but when it occurs in women, it is most often seen in the latter part of pregnancy. Though fracture is a rare complication of TOH when it occurs, it is most often associated with TOH occurring in pregnancy. Magnetic resonance imaging (MRI) is the best method to diagnosis TOH. Low signal intensity on T1-weighted images, high signal intensity on T2-weighted images, and homogenous pattern of edema (the femoral head and/or neck) with normal subchondral area are in favor of TOH. A shortened course to recovery is reported by use of bisphosphonates, calcitonin, or teriparatide. Based on reported cases, core decompression is not superior to medical therapy. Transient osteoporosis of the hip, which often has no known etiology, usually resolves with conservative therapy but may predispose the patient to fracture or avascular necrosis. Diagnostic method of choice is magnetic resonance imaging. Bisphosphonates, calcitonin, or teriparatide are reported as a useful approach to reduce duration of recovery.
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Abbreviations
- AVN:
-
avascular necrosis
- BMD:
-
bone mineral density
- BME:
-
bone marrow edema
- BMES:
-
Bone marrow edema syndrome
- DXA:
-
dual-energy X-ray absorptiometry
- PTH:
-
parathyroid hormone
- PTH-rP:
-
parathyroid hormone-related peptide
- RMO:
-
regional migratory osteoporosis
- STIR:
-
short-tau inversion recovery
- TOH:
-
transient osteoporosis of the hip
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Acknowledgements
The authors express their appreciation to Namrata Gumaste, divisional assistant, NYU Langone Medical Center, for a helpful revision of this manuscript.
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The abstract of part of this study has been presented as an oral presentation at the American Society of Bone and Mineral Research (ASBMR), September 12–14, 2014, Houston, TX [1].
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Asadipooya, K., Graves, L. & Greene, L.W. Transient osteoporosis of the hip: review of the literature. Osteoporos Int 28, 1805–1816 (2017). https://doi.org/10.1007/s00198-017-3952-0
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DOI: https://doi.org/10.1007/s00198-017-3952-0