Osteoporosis International

, Volume 16, Issue 12, pp 1823–1826

Reporting of vertebral fractures on spine X-rays

  • J. Fechtenbaum
  • C. Cropet
  • S. Kolta
  • B. Verdoncq
  • P. Orcel
  • C. Roux
Original Article

DOI: 10.1007/s00198-005-1939-8

Cite this article as:
Fechtenbaum, J., Cropet, C., Kolta, S. et al. Osteoporos Int (2005) 16: 1823. doi:10.1007/s00198-005-1939-8

Abstract

Vertebral fractures are the hallmark of osteoporosis, responsible for increased morbidity and mortality in post-menopausal women. However, two-thirds of vertebral fractures do not come to clinical attention. The aim of this study was to compare the identification of vertebral fractures on spine X-rays among rheumatologists. Study subjects were women aged 60–80 years having potential signs of vertebral fracture and visiting a rheumatologist. X-rays were performed according to standardized procedures. In 629 patients (among 824 included) at least one vertebral fracture was diagnosed, and the X-rays were then sent to a central facility where a semi-quantitative assessment of vertebral fracture was performed by a single rheumatologist trained for this evaluation. According to the vertebral level, kappa scores were between 0.20 to 0.77, i.e., below 0.6 from T4 to T7, and between 0.6 and 0.77 from T8 to L4. The false-negative fractures rate was 25.8% (and 15.7% of them were related to a numbering discrepancy). The rate of false positive fractures was 6.3%. At the patient level 6.8% had actually no fracture. This study shows that 25% of overall vertebral fractures are not diagnosed among patients considered as having at least one fracture. As a consequence, patients who require treatment to reduce fracture risk are not being properly identified.

Keywords

Diagnosis of osteoporosisOsteoporosisVertebral fracture

Copyright information

© International Osteoporosis Foundation and National Osteoporosis Foundation 2005

Authors and Affiliations

  • J. Fechtenbaum
    • 1
  • C. Cropet
    • 2
  • S. Kolta
    • 1
  • B. Verdoncq
    • 3
  • P. Orcel
    • 4
  • C. Roux
    • 1
  1. 1.Department of RheumatologyParis 5 University AP-HP Cochin HospitalParisFrance
  2. 2.MAPILyonFrance
  3. 3.AventisParisFrance
  4. 4.Rheumatology DepartmentAP-HP Lariboisière Hospital, Paris 7 UniversityParisFrance