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Steroid-induced femoral head osteonecrosis in immune thrombocytopenia treatment with osteochondral autograft transplantation

  • Hip
  • Published:
Knee Surgery, Sports Traumatology, Arthroscopy Aims and scope

Abstract

Osteonecrosis of the femoral head is a devastating complication of steroid administration and has rarely been observed in the treatment of immune thrombocytopenia. The treatment of osteochondral defects in advanced stages of avascular necrosis (AVN), characterized by collapse of the subchondral bone, remains an unsolved burden in orthopedic surgery. In this report, we present a case of a 19-year-old female that was admitted in the Emergency Department with walking disability and painful hip joint movement due to steroid-induced femoral head osteonecrosis. Two years before she was diagnosed with immune thrombocytopenia, for which she received pulse steroid therapy with high dose of dexamethasone and underwent a splenectomy. This case report is the first to describe the use of osteochondral autograft transplantation as a treatment of steroid-induced AVN of the femoral head due to immune thrombocytopenia at the age of 19 years with very good clinical and radiological results 3 years postoperatively.

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Conflict of interest

The authors declare that they have no conflicts of interest.

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Authors and Affiliations

  1. “Evangelismos” General Hospital of Athens, 45-47 Ipsilantou Str., 10676, Athens, Greece

    Vasileios Ch. Fotopoulos, George Mouzopoulos, Themistoklis Floros & Matthaios Tzurbakis

  2. Athens Medical Group, Peristeri Clinic, 60 Ethnarchou Makariou Str., 12132, Peristeri, Greece

    Vasileios Ch. Fotopoulos

  3. General Hospital of Cephalonia, Sweden Str., 28100, Argostoli, Greece

    George Mouzopoulos

  4. 69 Kyprou Avenue, Argyroupoli, 16451, Greece

    Vasileios Ch. Fotopoulos

Authors
  1. Vasileios Ch. Fotopoulos
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  2. George Mouzopoulos
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  3. Themistoklis Floros
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  4. Matthaios Tzurbakis
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Correspondence to Vasileios Ch. Fotopoulos.

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Fotopoulos, V.C., Mouzopoulos, G., Floros, T. et al. Steroid-induced femoral head osteonecrosis in immune thrombocytopenia treatment with osteochondral autograft transplantation. Knee Surg Sports Traumatol Arthrosc 23, 2605–2610 (2015). https://doi.org/10.1007/s00167-014-3239-3

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  • DOI: https://doi.org/10.1007/s00167-014-3239-3

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