Chest compressions versus ventilation plus chest compressions in a pediatric asphyxial cardiac arrest animal model
Rent the article at a discountRent now
* Final gross prices may vary according to local VAT.Get Access
To compare the ventilation achieved with chest compressions (CC) or ventilation plus compressions (VC) in a pediatric animal model of cardiac arrest.
Randomized experimental study.
Experimental department of a University Hospital.
Twelve infant pigs with asphyxial cardiac arrest. Sequential 3-min periods of VC and CC were performed for a total duration of 9 min. Tidal volume (TV), end-tidal CO2 (EtCO2), mean arterial pressure (MAP), central venous pressure (CVP), mean pulmonary arterial pressure (mPAP), and peripheral, cerebral, and renal saturations were recorded and arterial and venous blood gases were analyzed.
VC achieved a TV similar to the preset parameters on the ventilator, whilst the TV in CC was very low (P < 0.001). EtCO2 with VC was significantly higher than with CC (14.0 vs. 3.9 mmHg, P < 0.05). Arterial pH was higher with VC than with CC (6.99 vs. 6.90 mmHg, P < 0.05). Arterial PCO2 was lower with VC than with CC (62.1 vs. 97.0 mmHg, P < 0.05). There were no significant differences in the MAP; CVP; mPAP; peripheral, renal, and cerebral saturations; or lactate concentrations between the two techniques.
VC achieves better ventilation than CC during cardiopulmonary resuscitation and has no negative effect on the hemodynamic situation.
- The International Liaison Committee on Resuscitation (ILCOR) consensus on science with treatment recommendations for pediatric and neonatal patients: pediatric basic and advanced life support. Pediatrics 117: pp. e955-e977 CrossRef
- Sherman, M (2007) The new American Heart Association cardiopulmonary resuscitation guidelines: should children and adults have to share?. Curr Opin Pediatr 19: pp. 253-257 CrossRef
- Ewy, GA, Zuercher, M, Hilwig, RW, Sanders, AB, Berg, RA, Otto, CW, Hayes, MM, Kern, KB (2007) Improved neurological outcome with continuous chest compressions compared with 30:2 compressions-to-ventilations cardiopulmonary resuscitation in a realistic swine model of out-of-hospital cardiac arrest. Circulation 116: pp. 2525-2530 CrossRef
- Berg, RA, Kern, KB, Hilwig, RW, Berg, MD, Sanders, AB, Otto, CW, Ewy, GA (1997) Assisted ventilation does not improve outcome in a porcine model of single-rescuer bystander cardiopulmonary resuscitation. Circulation 95: pp. 1635-1641
- Berg, RA, Kern, KB, Sanders, AB, Otto, CW, Hilwig, RW, Ewy, GA (1993) Bystander cardiopulmonary resuscitation: is ventilation necessary?. Circulation 88: pp. 1907-1915
- Noc, M, Weil, MH, Tang, W, Turner, T, Fukui, M (1995) Mechanical ventilation may not be essential for initial cardiopulmonary resuscitation. Chest 108: pp. 821-827 CrossRef
- Kern, KB, Hilwig, RW, Berg, RA, Ewy, GA (1998) Efficacy of chest compression-only BLS CPR in the presence of an occluded airway. Resuscitation 39: pp. 179-188 CrossRef
- Chandra, NC, Gruben, KG, Tsitlik, JE, Brower, R, Guerci, AD, Halperin, HH, Weisfeldt, ML, Permutt, S (1994) Observations of ventilation during resuscitation in a canine model. Circulation 90: pp. 3070-3075
- Cardiopulmonary resuscitation by bystanders with chest compression only (SOS-KANTO): an observational study. Lancet 369: pp. 920-926 CrossRef
- Iwami, T, Kawamura, T, Hiraide, A, Berg, RA, Hayashi, Y, Nishiuchi, T, Kajino, K, Yonemoto, N, Yukioka, H, Sugimoto, H, Kakuchi, H, Sase, K, Yokoyama, H, Nonogi, H (2007) Effectiveness of bystander-initiated cardiac-only resuscitation for patients with out-of-hospital cardiac arrest. Circulation 116: pp. 2900-2907 CrossRef
- Ong, ME, Ng, FS, Anushia, P, Tham, LP, Leong, BS, Ong, VY, Tiah, L, Lim, SH, Anantharaman, V (2008) Comparison of chest compression only and standard cardiopulmonary resuscitation for out-of-hospital cardiac arrest in Singapore. Resuscitation 78: pp. 119-126 CrossRef
- Berg, RA, Hilwig, RW, Kern, KB, Babar, I, Ewy, GA (1999) Simulated mouth-to-mouth ventilation and chest compressions (bystander cardiopulmonary resuscitation) improves outcome in a swine model of prehospital pediatric asphyxial cardiac arrest. Crit Care Med 27: pp. 1893-1899 CrossRef
- Berg, RA, Hilwig, RW, Kern, KB, Ewy, GA (2000) Bystander chest compressions and assisted ventilation independently improve outcome from piglet asphyxial pulseless cardiac arrest. Circulation 101: pp. 1743-1748
- Berg, RA (2000) Role of mouth-to-mouth rescue breathing in bystander cardiopulmonary resuscitation for asphyxial cardiac arrest. Crit Care Med 28: pp. 193-195 CrossRef
- Idris, AH, Banner, MJ, Wenzel, V, Fuerst, RS, Becker, LB, Melker, RJ (1994) Ventilation caused by external chest compression is unable to sustain effective gas exchange during CPR: a comparison with mechanical ventilation. Resuscitation 28: pp. 143-150 CrossRef
- Deakin, CD, O’Neill, JF, Tabor, T (2007) Does compression-only cardiopulmonary resuscitation generate adequate passive ventilation during cardiac arrest?. Resuscitation 75: pp. 53-59 CrossRef
- Bobrow, BJ, Zuercher, M, Ewy, GA, Clark, L, Chikani, V, Donahue, D, Sanders, AB, Hilwig, RW, Berg, RA, Kern, KB (2008) Gasping during cardiac arrest in humans is frequent and associated with improved survival. Circulation 118: pp. 2550-2554 CrossRef
- Dorph, E, Wik, L, Stromme, TA, Eriksen, M, Steen, PA (2004) Oxygen delivery and return of spontaneous circulation with ventilation: compression ratio 2:30 versus chest compressions only CPR in pigs. Resuscitation 60: pp. 309-318 CrossRef
- Steen, PA (2007) Does active rescuer ventilation have a place during basic cardiopulmonary resuscitation?. Circulation 116: pp. 2514-2516 CrossRef
- Lurie, KG, Yannopoulos, D, McKnite, SH, Herman, ML, Idris, AH, Nadkarni, VM, Tang, W, Gabrielli, A, Barnes, TA, Metzger, AK (2008) Comparison of a 10-breaths-per-minute versus a 2-breaths-per-minute strategy during cardiopulmonary resuscitation in a porcine model of cardiac arrest. Respir Care 53: pp. 862-870
- Chest compressions versus ventilation plus chest compressions in a pediatric asphyxial cardiac arrest animal model
Intensive Care Medicine
Volume 36, Issue 4 , pp 712-716
- Cover Date
- Print ISSN
- Online ISSN
- Additional Links
- Cardiac arrest
- Chest compressions
- Industry Sectors