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Pediatric Index of Mortality 2 score in Italy: a multicenter, prospective, observational study

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Abstract

Objectives

To assess the performance of the Pediatric Index of Mortality (PIM) 2 score in Italian pediatric intensive care units (PICUs).

Design

Prospective, observational, multicenter, 1-year study.

Setting

Eighteen medical–surgical PICUs.

Patients

Consecutive patients (3266) aged 0–16 years admitted between 1 March 2004 and 28 February 2005.

Interventions

None.

Measurements and main results

To assess the performance of the PIM2 score, discrimination and calibration measures were applied to all children admitted to the 18 PICUs, in the entire population and in different groups divided for deciles of risk, age and admission diagnosis. There was good discrimination, with an area under the receiver operating characteristic (ROC) curve of 0.89 (95% CI 0.86–0.91) and good calibration of the scoring system [non-significant differences between observed and predicted deaths when the population was stratified according to deciles of risk (χ2 9.86; 8 df, p = 0.26) for the whole population].

Conclusions

The PIM2 score performed well in this sample of the Italian pediatric intensive care population. It may need to be reassessed in the injury and postoperative groups in larger studies.

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Author information

Authors and Affiliations

  1. Department of Anesthesia and Intensive Care, Children’s Hospital Vittore Buzzi, Istituti Clinici di Perfezionamento, Via Castelvetro 32, 20154, Milan, Italy

    Andrea Wolfler, Paolo Silvani & Ida Salvo

  2. National Research Council, Institute of Biomedical Technologies, IRCCS “Fondazione Santa Lucia”, Rome, Italy

    Massimo Musicco

Authors
  1. Andrea Wolfler
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  2. Paolo Silvani
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  3. Massimo Musicco
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  4. Ida Salvo
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Consortia

Italian Pediatric Sepsis Study (SISPe) Group

Corresponding author

Correspondence to Andrea Wolfler.

Additional information

The members of the SISPe group are listed in the appendix.

Members of the Italian Pediatric Sepsis Study (SISPe) Group

Members of the Italian Pediatric Sepsis Study (SISPe) Group

P. Vitale, A. Conio (Ospedale Regina Margherita, Turin); G. Ottonello, A. Arena (Ospedale Gaslini, Genoa); C. Gallini, R. Gilodi (Ospedale Sant'Antonio e Biagio e Cesare Arrigo, Alessandria); R. Osello, F. Ferrero (Ospedale Maggiore della Carità, Novara); E. Zoia, A. Mandelli (Ospedale de Bambini V Buzzi, Milan); L. Napolitano, S. Leoncino (Fondazione Ospedale Maggiore Policlinico Mangiagalli Regina Elena, Milan); E. Galassini (Ospedale Fatebenefratelli, Milan); D. Codazzi (Ospedali Riuniti, Bergamo); A. Baraldi, S. Molinaro (Spedali Civili, Brescia); P. Santuz (Ospedale Civile Borgo Trento, Verona); P. Cogo, A. Pettenazzo (Ospedale Civile T.I. Pediatrica, Padua); L. Meneghini, F. Giusti (Ospedale Civile Anestesia, Padua); A. Sarti (Ospedale Burlo, Trieste); E. Iannella, S. Baroncini (Ospedale Sant'Orsola Malpigli, Bologna); M. Calamandrei, A. Messeri (Ospedale Meyer, Florence); M. Marano, C. Tomasello (Ospedale Bambin Gesù DEA, Rome); A. Onofri, M. Ferrari (Ospedale Bambin Gesù Anestesia, Rome); M. Piastra, E. Caresta (Ospedale Gemelli, Rome); A. Dolcini (Ospedale Santo Bono, Naples); C. Rovella, A.M. Guddo (Ospedale G.A. Di Cristina, Palermo); M. Astuto, N. Disma (Ospedale Policlinico, Catania); D. Salvo, D. Buono (Ospedale San Vincenzo, Taormina)

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Wolfler, A., Silvani, P., Musicco, M. et al. Pediatric Index of Mortality 2 score in Italy: a multicenter, prospective, observational study. Intensive Care Med 33, 1407–1413 (2007). https://doi.org/10.1007/s00134-007-0694-z

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  • DOI: https://doi.org/10.1007/s00134-007-0694-z

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