Abstract
This study investigated the effects of the polybrominated diphenyl ether congener, 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) on the growth and development, and subsequent breeding success of exposed zebra finches (Taeniopygia guttata). Using oral dosing procedures and treatments adjusted by weight, we treated newly hatched chicks daily for the first 20-days-post-hatch (dph) with varying treatments of BDE-47 (0, 5, 50, and 500 ng/g bw/day). Weight and tarsal measurements were monitored from hatch to 90 dph, but no differences were observed between treatment groups at any age. Treated females that reached sexual maturity were mated with untreated males; however, again no treatment effects were observed on breeding success. Analysis of tissue samples at 21 dph did indicate that debromination of BDE-47 had occurred resulting in BDE-28 and BDE-17 metabolites.
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An J, Yin L, Shang Y, Zhong Y, Zhang X, Wu M, Yu Z, Sheng G, Fu J, Huang Y (2011) The combined effects of BDE47 and BaP on oxidatively generated DNA damage in L02 cells and the possible molecular mechanism. Mutat Res\Genet Environ Mutagen 721:192–198
Chen D, Hale RC (2010) A global review of polybrominated diphenyl ether flame retardant contamination in birds. Environ Int 36:800–811
Darnerud PO (2003) Toxic effects of brominated flame retardants in man and in wildlife. Environ Int 29:841–853
Eens M, Jaspers VLB, Van den Steen E, Bateson M, Carere C, Clergeau P, Costantini D, Dolenec Z, Elliott JE, Flux J, Gwinner H, Halbrook RS, Heeb P, Mazgajski TD, Moksnes A, Polo V, Soler JJ, Sinclair R, Veiga JP, Williams TD, Covaci A, Pinxten R (2013) Can starling eggs be useful as a biomonitoring tool to study organohalogenated contaminants on a worldwide scale? Environ Int 51:141–149
Elliott JE, Wilson LK, Wakeford B (2005) Polybrominated diphenyl ether trends in eggs of marine and freshwater birds from British Columbia, Canada, 1979–2002. Environ Sci Technol 39:5584–5590
Eng ML, Elliott JE, MacDougall-Shackleton SA, Letcher RJ, Williams TD (2012) Early exposure to 2,2′,4,4′,5-pentabromodiphenyl ether (BDE-99) affects mating behavior of zebra finches. Toxicol Sci 127:269–276
Eng ML, Williams TD, Elliott JE (2013) Developmental exposure to a brominated flame retardant: an assessment of effects on physiology, growth, and reproduction in a songbird, the zebra finch. Environ Pollut 178:343–349
Eriksson P, Viberg H, Jakobsson E, Orn U, Frederiksson A (2002) A brominated flame retardant, 2,2′,4,4′,5-pentabromodiphenyl ether: uptake, retention, and induction of neurobehavioral alterations in mice during a critical phase of neonatal brain development. Toxicol Sci 67:98–103
Fernie KJ, Shutt JL, Ritchie IJ, Letcher RJ, Drouillard K, Bird DM (2006) Changes in the growth, but not the survival of American kestrels (Falco sparverius) exposed to environmentally relevant polybrominated diphenyl ethers. J Toxicol Environ Health, Part A 69:1541–1554
Gascon M, Vrijheid M, Martinez D, Forns J, Grimalt JO, Torrent M, Sunyer J (2011) Effects of pre and postnatal exposure to low levels of polybromodiphenyl ethers on neurodevelopment and thyroid hormone levels at 4 years of age. Environ Int 37:605–611
Haraguchi K, Hisamichi Y, Endo T (2009) Accumulation and mother-to-calf transfer of anthropogenic and natural organohalogens in killer whales (Orcinus orca) stranded on the Pacific coast of Japan. Sci Total Environ 407:2853–2859
Herbstman JB, Sjodin A, Kurzon M, Lederman SA, Jones RS, Rauh V, Needham LL, Tang D, Niedzwiecki M, Wang RY, Perera F (2010) Prenatal exposure to PBDEs and neurodevelopment. Environ Health Perspect 118:712-719
Jaspers VLB, Covaci A, Voorspoels S, Dauwe T, Eens M, Schepens P (2006) Brominated flame retardants and organochlorine pollutants in aquatic and terrestrial predatory birds of Belgium: levels, patterns, tissue distribution and condition factors. Environ Pollut 139:340–352
McKernan MA, Rattner BA, Hale RC, Ottinger MA (2009) Toxicity of polybrominated diphenyl ethers (de-71) in chicken (Gallus gallus), mallard (Anus platyrhynchos), and American kestrel (Falco sparverius) embryos and hatchings. Environ Toxicol and Chem 28:1007–1017
She J, Holden A, Adelsbach TL, Tanner M, Schwarzbach SE, Yee JL, Hooper K (2008) Concentrations and time trends of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) in aquatic bird eggs from San Francisco Bay, CA 2000–2003. Chemosphere 73:S201–S209
Stapleton HM, Klosterhaus S, Eagle S, Fuh J, Meeker JD, Blum A, Webster TF (2009) Detection of organophosphate flame retardants in furniture foam and U.S. house dust. Environ Sci Technol 43:7490–7495
Tokarz JAIII, Ahn M-Y, Leng J, Filley TR, Nies L (2008) Reductive debromination of polybrominated diphenyl ethers in anaerobic sediment and a biomimetic system. Environ Sci Technol 42:1157–1164
Ucan Marin F, Arukwe A, Mortensen A, Gabrielsen GW, Fox GA, Letcher RJ (2009) Recombinant transthyretin purification and competitive binding with organohalogen compounds in two gull species (Larus argentatus and Larus hyperboreus). Toxicol Sci 107:440–450
Vonderheide AP (2009) A review of the challenges in the chemical analysis of the polybrominated diphenyl ethers. Microchem J 92:49–57
Winter V, Williams TD, Elliott JE (2013) A three-generational study of in ovo exposure to PBDE-99 in the zebra finch. Environ Toxicol Chem 32:562–568
Zhang K, Wan Y, Giesy JP, Lam MHW, Wiseman S, Jones PD, Hu J (2010) Tissue concentrations of polybrominated compounds in Chinese sturgeon (Acipenser sinensis): origin, hepatic sequestration, and maternal transfer. Environ Sci Technol 201:5781–5786
Acknowledgments
This study was financially supported by the Chemical Management Plan (CMP; Environment Canada). We would like to thank Lewis Gauthier in the Organic Contaminants Research Laboratory (OCRL) in the National Wildlife Research Center, Environment Canada for the PBDE analysis.
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Currier, H.A., Letcher, R.J., Williams, T.D. et al. Effects of the Bioaccumulative Polybrominated Diphenyl Ether Flame Retardant Congener BDE-47 on Growth, Development, and Reproductive Success in Zebra Finches. Bull Environ Contam Toxicol 94, 140–145 (2015). https://doi.org/10.1007/s00128-014-1393-4
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DOI: https://doi.org/10.1007/s00128-014-1393-4