Skip to main content

Advertisement

Log in

Risk of suicide according to level of psychiatric treatment: a nationwide nested case–control study

  • Original Paper
  • Published:
Social Psychiatry and Psychiatric Epidemiology Aims and scope Submit manuscript

Abstract

Purpose

Knowledge of the epidemiology of suicide is a necessary prerequisite of suicide prevention. We aimed to conduct a nationwide study investigating suicide risk in relation to level of psychiatric treatment.

Methods

Nationwide nested case–control study comparing individuals who died from suicide between 1996 and 2009 to age-, sex-, and year-matched controls. Psychiatric treatment in the previous year was graded as “no treatment,” “medicated,” “outpatient contact,” “psychiatric emergency room contact,” or “admitted to psychiatric hospital.”

Results

There were 2,429 cases and 50,323 controls. Compared with people who had not received any psychiatric treatment in the preceding year, the adjusted rate ratio (95 % confidence interval) for suicide was 5.8 (5.2–6.6) for people receiving only psychiatric medication, 8.2 (6.1–11.0) for people with at most psychiatric outpatient contact, 27.9 (19.5–40.0) for people with at most psychiatric emergency room contacts, and 44.3 (36.1–54.4) for people who had been admitted to a psychiatric hospital. The gradient was steeper for married or cohabiting people, those with higher socioeconomic position, and possibly those without a history of attempted suicide.

Conclusions

Psychiatric admission in the preceding year was highly associated with risk of dying from suicide. Furthermore, even individuals who have been in contact with psychiatric treatment but who have not been admitted are at highly increased risk of suicide.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. World Health Organization. Suicide prevention (SUPRE). http://www.whoint/mental_health/prevention/suicide/suicideprevent/en/2012. Cited 2013 Aug 26. http://www.who.int/mental_health/prevention/suicide/suicideprevent/en/

  2. Mortensen PB, Agerbo E, Erikson T, Qin P, Westergaard-Nielsen N (2000) Psychiatric illness and risk factors for suicide in Denmark. Lancet 355(9197):9–12

    Article  CAS  PubMed  Google Scholar 

  3. Bostwick JM, Pankratz VS (2000) Affective disorders and suicide risk: a reexamination. Am J Psychiatry 157(12):1925–1932

    Article  CAS  PubMed  Google Scholar 

  4. Palmer BA, Pankratz VS, Bostwick JM (2005) The lifetime risk of suicide in schizophrenia: a reexamination. Arch Gen Psychiatry 62(3):247–253

    Article  PubMed  Google Scholar 

  5. Harris EC, Barraclough B (1997) Suicide as an outcome for mental disorders. A meta-analysis. Br J Psychiatry 170:205–228

    Article  CAS  PubMed  Google Scholar 

  6. Goldacre M, Seagroatt V, Hawton K (1993) Suicide after discharge from psychiatric inpatient care. Lancet 342(8866):283–286

    Article  CAS  PubMed  Google Scholar 

  7. Pirkis J, Burgess P (1998) Suicide and recency of health care contacts. A systematic review. Br J Psychiatry 173:462–474

    Article  CAS  PubMed  Google Scholar 

  8. Qin P, Nordentoft M (2005) Suicide risk in relation to psychiatric hospitalization: evidence based on longitudinal registers. Arch Gen Psychiatry 62(4):427–432

    Article  PubMed  Google Scholar 

  9. Madsen T, Agerbo E, Mortensen PB, Nordentoft M (2011) Predictors of psychiatric inpatient suicide: a national prospective register-based study. J Clin Psychiatry 73(2):144–151

    Google Scholar 

  10. Agerbo E (2007) High income, employment, postgraduate education, and marriage: a suicidal cocktail among psychiatric patients. Arch Gen Psychiatry 64(12):1377–1384

    Article  PubMed  Google Scholar 

  11. Hunt IM, Kapur N, Webb R, Robinson J, Burns J, Turnbull P et al (2007) Suicide in current psychiatric in-patients: a case-control study. The National Confidential Inquiry into Suicide and Homicide. Psychol Med 37(6):831–837

    Article  PubMed  Google Scholar 

  12. Pedersen CB (2011) The Danish civil registration system. Scand J Public Health 39(7 suppl):22–25

    Article  PubMed  Google Scholar 

  13. Helweg-Larsen K (2011) The Danish register of causes of death. Scand J Public Health 39(7 Suppl):26–29

    Article  PubMed  Google Scholar 

  14. Borgan O, Goldstein L, Langholz B (1995) Methods for the analysis of sampled cohort data in the Cox proportional hazards model. Ann Stat 23(5):1749–1778

    Article  Google Scholar 

  15. McDowall M (1983) Adjusting proportional mortality ratios for the influence of extraneous causes of death. Stat Med 2(4):467–475

    Article  CAS  PubMed  Google Scholar 

  16. Roman E, Beral V, Inskip H, McDowall M, Adelstein A (1984) A comparison of standardized and proportional mortality ratios. Stat Med 3(1):7–14

    Article  CAS  PubMed  Google Scholar 

  17. Mors O, Perto GP, Mortensen PB (2011) The Danish psychiatric central research register. Scand J Public Health 39(7 Suppl):54–57

    Article  PubMed  Google Scholar 

  18. Kildemoes HW, Sorensen HT, Hallas J (2011) The Danish national prescription registry. Scand J Public Health 39(7 Suppl):38–41

    Article  PubMed  Google Scholar 

  19. Statistics Denmark (2007) Integrated database for labour market research (IDA). Statistics Denmark. Cited 2013 Aug 26. http://www.dst.dk/en/Statistik/dokumentation/Declarations/integrated-database-for-labour-market-research-ida-.aspx

  20. Christiansen E, Larsen KJ, Agerbo E, Bilenberg N, Stenager E (2012) Incidence and risk factors for suicide attempts in a general population of young people: a Danish register-based study. Aust N Z J Psychiatry

  21. Borgan O, Langholz B (1993) Nonparametric estimation of relative mortality from nested case-control studies. Biometrics 49(2):593–602

    Article  CAS  PubMed  Google Scholar 

  22. King G, Zeng L (2002) Estimating risk and rate levels, ratios and differences in case-control studies. Stat Med 21(10):1409–1427

    Article  PubMed  Google Scholar 

  23. Bjerregaard P, Curtis T (2002) Cultural change and mental health in Greenland: the association of childhood conditions, language, and urbanization with mental health and suicidal thoughts among the Inuit of Greenland. Soc Sci Med 54(1):33–48

    Article  PubMed  Google Scholar 

  24. Moustgaard H, Bjerregaard P, Borch-Johnsen K, Jorgensen ME (2005) Diabetes among Inuit migrants in Denmark. Int J Circumpolar Health 64(4):354–364

    Article  PubMed  Google Scholar 

  25. Boysen T, Friborg J, Andersen A, Nilsson Poulsen G, Wohlfahrt J, Melbye M (2008) The Inuit cancer pattern—the influence of migration. Int J Cancer 122(11):2568–2572

    Article  CAS  PubMed  Google Scholar 

  26. Hugo M, Smout M, Bannister J (2002) A comparison in hospitalization rates between a community-based mobile emergency service and a hospital-based emergency service. Aust N Z J Psychiatry 36(4):504–508

    Article  PubMed  Google Scholar 

  27. Schnyder U, Klaghofer R, Leuthold A, Buddeberg C (1999) Characteristics of psychiatric emergencies and the choice of intervention strategies. Acta Psychiatr Scand 99(3):179–187

    Article  CAS  PubMed  Google Scholar 

  28. Baca-Garcia E, Diaz-Sastre C, Resa EG, Blasco H, Conesa DB, Saiz-Ruiz J et al (2004) Variables associated with hospitalization decisions by emergency psychiatrists after a patient’s suicide attempt. Psychiatr Serv 55(7):792–797

    Article  PubMed  Google Scholar 

  29. Kapusta ND, Tran US, Rockett IR, De LD, Naylor CP, Niederkrotenthaler T et al (2011) Declining autopsy rates and suicide misclassification: a cross-national analysis of 35 countries. Arch Gen Psychiatry 68(10):1050–1057

    Article  PubMed  Google Scholar 

  30. Atkinson MW, Kessel N, Dalgaard JB (1975) The comparability of suicide rates. Br J Psychiatry 127:247–256

    Article  CAS  PubMed  Google Scholar 

  31. De Leo D, Evans R (2003) International suicide rates: recent trends and implications for Australia. Australian Institute for Suicide Research and Prevention, Canberra

    Google Scholar 

Download references

Acknowledgments

The study was funded by The Ministry of Social Affairs. The authors have no conflict of interest to report, and the funding organization had no role in design or conduct of the study; collection, management, analysis, or interpretation of the data; or preparation, review, or approval of the manuscript.

Conflict of interest

All authors declare that we have no conflict of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Carsten Rygaard Hjorthøj.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hjorthøj, C.R., Madsen, T., Agerbo, E. et al. Risk of suicide according to level of psychiatric treatment: a nationwide nested case–control study. Soc Psychiatry Psychiatr Epidemiol 49, 1357–1365 (2014). https://doi.org/10.1007/s00127-014-0860-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00127-014-0860-x

Keywords

Navigation