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S2k-Leitlinie zur Diagnostik, Therapie und Metaphylaxe der Urolithiasis (AWMF 043/025)

Kurzfassung

S2k guidelines on diagnostics, therapy and metaphylaxis of urolithiasis (AWMF 043/025)

Compendium

  • Leitlinien der DGU
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Zusammenfassung

Jeder 10. Bundesbürger wird im Laufe seines Lebens zumindest einen Harnstein bilden. Die Diagnostik, Therapie und Nachsorge der Urolithiasis gehört daher zum täglich Brot aller Urologen in Klinik und Praxis, aber auch vieler anderer Fachdisziplinen wie Allgemeinmedizinern, Internisten, Nephrologen oder Pädiatern. Während Diagnostik und Therapie in den letzten 10 Jahren erhebliche Veränderungen erfahren haben, fristen die Möglichkeiten einer metabolischen Diagnostik und Sekundärprävention von Risikopatienten leider vielerorts – zu Unrecht – ein Schattendasein. Die vorliegende S2k-Leitlinie, welche erstmals aus einem interdisziplinären Konsensusprozess hervorging, stellt die aktuellen Empfehlungen praxisnah dar und verwendet wann immer möglich Tabellen und Algorithmen, um ein rasches Nachschlagen bei der täglichen Arbeit zu erleichtern. Nicht zuletzt die Maßnahmen zur Metaphylaxe werden hierdurch deutlich vereinfacht.

Abstract

Every tenth German citizen will suffer from at least one urinary calculus during the lifetime. The diagnostics, treatment and follow-up treatment of urolithiasis are, therefore, part of the daily routine practice for all urologists in hospitals and private practices as well as in many other disciplines, such as general practitioners, internists, nephrologists and pediatricians. Although the diagnostics and therapy have experienced substantial alterations over the last 10 years, the possibilities of metabolic diagnostics and secondary prevention for patients at risk are, unfortunately and unjustly, in many places very poorly represented. The present S2k guidelines, which for the first time were established in an interdisciplinary consensus process, represent the current practical recommendations and, whenever possible, use tables and algorithms in order to facilitate easy reference in the routine daily work. Last but not least, this greatly simplifies the measures for metaphylaxis.

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Literatur

  1. Erwin BC, Carroll BA, Sommer FG (1985) Re: US in the evaluation of acute flank pain. Radiology 157:554

    Article  CAS  PubMed  Google Scholar 

  2. Varma G, Nair N, Salim A, Marickar YM (2009) Investigations for recognizing urinary stone. Urol Res 37:349–352

    Article  PubMed  Google Scholar 

  3. Heidenreich A, Desgrandschamps F, Terrier F (2002) Modern approach of diagnosis and management of acute flank pain: review of all imaging modalities. Eur Urol 41:351–362

    Article  PubMed  Google Scholar 

  4. Miller OF, Rineer SK, Reichard SR, Buckley RG, Donovan MS, Graham IR et al (1998) Prospective comparison of unenhanced spiral computed tomography and intravenous urogram in the evaluation of acute flank pain. Urology 52:982–987

    Article  CAS  PubMed  Google Scholar 

  5. Niall O, Russell J, MacGregor R, Duncan H, Mullins J (1999) A comparison of noncontrast computerized tomography with excretory urography in the assessment of acute flank pain. J Urol 161:534–537

    Article  CAS  PubMed  Google Scholar 

  6. Yilmaz S, Sindel T, Arslan G, Ozkaynak C, Karaali K, Kabaalioglu A et al (1998) Renal colic: comparison of spiral CT, US and IVU in the detection of ureteral calculi. Eur Radiol 8:212–217

    Article  CAS  PubMed  Google Scholar 

  7. Worster A, Preyra I, Weaver B, Haines T (2002) The accuracy of noncontrast helical computed tomography versus intravenous pyelography in the diagnosis of suspected acute urolithiasis: a meta-analysis. Ann Emerg Med 40:280–286

    Article  PubMed  Google Scholar 

  8. El-Nahas AR, El-Assmy AM, Mansour O, Sheir KZ (2007) A prospective multivariate analysis of factors predicting stone disintegration by extracorporeal shock wave lithotripsy: the value of high-resolution noncontrast computed tomography. Eur Urol 51:1688–1693 (discussion 93-4)

    Article  PubMed  Google Scholar 

  9. Patel M, Han SS, Vaux K, Saalfeld J, Alexander JH (2000) A protocol of early spiral computed tomography for the detection of stones in patients with renal colic has reduced the time to diagnosis and overall management costs. Aust N Z J Surg 70:39–42

    Article  CAS  PubMed  Google Scholar 

  10. Jellison FC, Smith JC, Heldt JP, Spengler NM, Nicolay LI, Ruckle HC et al (2009) Effect of low dose radiation computerized tomography protocols on distal ureteral calculus detection. J Urol 182:2762–2767

    Article  PubMed  Google Scholar 

  11. Kluner C, Hein PA, Gralla O, Hein E, Hamm B, Romano V et al (2006) Does ultra-low-dose CT with a radiation dose equivalent to that of KUB suffice to detect renal and ureteral calculi? J Comput Assist Tomogr 30:44–50

    Article  PubMed  Google Scholar 

  12. Caoili EM, Cohan RH, Korobkin M, Platt JF, Francis IR, Faerber GJ et al (2002) Urinary tract abnormalities: initial experience with multi-detector row CT urography. Radiology 222:353–360

    Article  PubMed  Google Scholar 

  13. Van Der MAJ, Cowan NC, Mueller-Lisse UG, Nolte-Ernsting CC, Takahashi S, Cohan RH (2008) CT urography: definition, indications and techniques. A guideline for clinical practice. Eur Radiol 18:4–17

    Article  Google Scholar 

  14. Zwergel U, Felgner J, Rombach H, Zwergel T (1998) Current conservative treatment of renal colic: value of prostaglandin synthesis inhibitors. Schmerz 12:112–117

    Article  CAS  PubMed  Google Scholar 

  15. Bektas F, Eken C, Karadeniz O, Goksu E, Cubuk M, Cete Y (2009) Intravenous paracetamol or morphine for the treatment of renal colic: a randomized, placebo-controlled trial. Ann Emerg Med 54:568–574

    Article  PubMed  Google Scholar 

  16. Serinken M, Eken C, Turkcuer I, Elicabuk H, Uyanik E, Schultz CH (2012) Intravenous paracetamol versus morphine for renal colic in the emergency department: a randomised double-blind controlled trial. Emerg Med J 29:902:5

    Google Scholar 

  17. Holdgate A, Pollock T (2004) Systematic review of the relative efficacy of non-steroidal anti-inflammatory drugs and opioids in the treatment of acute renal colic. BMJ 328:1401

    Article  PubMed  PubMed Central  Google Scholar 

  18. Papadopoulos G, Bourdoumis A, Kachrilas S, Bach C, Buchholz N, Masood J (2014) Hyoscine N‑butylbromide (Buscopan) in the treatment of acute ureteral colic: What is the evidence. Urol Int 92(3):253–257

    Article  CAS  PubMed  Google Scholar 

  19. Edwards JE, McQuay HJ, Moore RA (2002) Combination analgesic efficacy: individual patient data meta-analysis of single-dose oral tramadol plus acetaminophen in acute postoperative pain. J Pain Symptom Manage 23:121–130

    Article  CAS  PubMed  Google Scholar 

  20. Ramsey S, Robertson A, Ablett MJ, Meddings RN, Hollins GW, Little B (2010) Evidence-based drainage of infected hydronephrosis secondary to ureteric calculi. J Endourol 24:185–189

    Article  PubMed  Google Scholar 

  21. Pearle MS, Pierce HL, Miller GL, Summa JA, Mutz JM, Petty BA et al (1998) Optimal method of urgent decompression of the collecting system for obstruction and infection due to ureteral calculi. J Urol 160:1260–1264

    Article  CAS  PubMed  Google Scholar 

  22. Mokhmalji H, Braun PM, Martinez Portillo FJ, Siegsmund M, Alken P, Kohrmann KU (2001) Percutaneous nephrostomy versus ureteral stents for diversion of hydronephrosis caused by stones: a prospective, randomized clinical trial. J Urol 165:1088

    Article  CAS  PubMed  Google Scholar 

  23. Miller OF, Kane CJ (1999) Time to stone passage for observed ureteral calculi: a guide for patient education. J Urol 162:688

    Article  CAS  PubMed  Google Scholar 

  24. Campschroer T, Zhu Y, Duijvesz D, Grobbee DE, Lock MT (2014) Alpha-blockers as medical expulsive therapy for ureteral stones. Cochrane Database Syst Rev 2014:CD008509

    Google Scholar 

  25. Seitz C, Liatsikos E, Porpiglia F, Tiselius HG, Zwergel U (2009) Medical therapy to facilitate the passage of stones: what is the evidence? Eur Urol 56:455–471

    Article  PubMed  Google Scholar 

  26. Hollingsworth JM, Rogers MA, Kaufman SR, Bradford TJ, Saint S, Wei JT et al (2006) Medical therapy to facilitate urinary stone passage: a meta-analysis. Lancet 368:1171–1179

    Article  PubMed  Google Scholar 

  27. Singh A, Alter HJ, Littlepage A (2007) A systematic review of medical therapy to facilitate passage of ureteral calculi. Ann Emerg Med 50:552–563

    Article  PubMed  Google Scholar 

  28. Skolarikos A, Laguna MP, Alivizatos G, Kural AR, Rosette JJ de la (2010) The role for active monitoring in urinary stones: a systematic review. J Endourol 24:923–930

    Article  CAS  PubMed  Google Scholar 

  29. Preminger GM, Tiselius HG, Assimos DG, Alken P, Buck AC, Gallucci M et al (2007) Guideline for the management of ureteral calculi. Eur Urol 2007(52):1610–1631

    Article  Google Scholar 

  30. Pareek G, Hedican SP, Lee FT Jr., Nakada SY (2005) Shock wave lithotripsy success determined by skin-to-stone distance on computed tomography. Urology 66:941–944

    Article  PubMed  Google Scholar 

  31. Fuller A, Razvi H, Denstedt JD, Nott L, Pearle M, Cauda F et al (2012) The CROES percutaneous nephrolithotomy global study: the influence of body mass index on outcome. J Urol 188:138–144

    Article  PubMed  Google Scholar 

  32. Sari E, Tepeler A, Yuruk E, Resorlu B, Akman T, Binbay M et al (2013) Effect of the body mass index on outcomes of flexible ureterorenoscopy. Urolithiasis 41:499–504

    Article  PubMed  Google Scholar 

  33. Watterson JD, Girvan AR, Cook AJ, Beiko DT, Nott L, Auge BK et al (2002) Safety and efficacy of holmium: YAG laser lithotripsy in patients with bleeding diatheses. J Urol 168:442–445

    Article  PubMed  Google Scholar 

  34. Kavanagh A, Afshar K, Scott H, MacNeily AE (2012) Bladder neck closure in conjunction with enterocystoplasty and Mitrofanoff diversion for complex incontinence: closing the door for good. J Urol 188:1561–1565

    Article  PubMed  Google Scholar 

  35. Klingler HC, Kramer G, Lodde M, Dorfinger K, Hofbauer J, Marberger M (2003) Stone treatment and coagulopathy. Eur Urol 43:75

    Article  CAS  PubMed  Google Scholar 

  36. Turna B, Stein RJ, Smaldone MC, Santos BR, Kefer JC, Jackman SV et al (2008) Safety and efficacy of flexible ureterorenoscopy and holmium:YAG lithotripsy for intrarenal stones in anticoagulated cases. J Urol 179:1415–1419

    Article  PubMed  Google Scholar 

  37. Kuo RL, Aslan P, Fitzgerald KB, Preminger GM (1998) Use of ureteroscopy and holmium:YAG laser in patients with bleeding diatheses. Urology 52:609–613

    Article  CAS  PubMed  Google Scholar 

  38. Argyropoulos AN, Tolley DA (2010) Evaluation of outcome following lithotripsy. Curr Opin Urol 20:154–158

    Article  PubMed  Google Scholar 

  39. Srisubat A, Potisat S, Lojanapiwat B, Setthawong V, Laopaiboon M (2009) Extracorporeal shock wave lithotripsy (ESWL) versus percutaneous nephrolithotomy (PCNL) or retrograde intrarenal surgery (RIRS) for kidney stones. Cochrane Database Syst Rev 2009:CD007044

    Google Scholar 

  40. Aboumarzouk OM, Monga M, Kata SG, Traxer O, Somani BK (2012) Flexible ureteroscopy and laser lithotripsy for stones 〉2 cm: a systematic review and meta-analysis. J Endourol 26:1257–1263

    Article  PubMed  Google Scholar 

  41. Sahinkanat T, Ekerbicer H, Onal B, Tansu N, Resim S, Citgez S et al (2008) Evaluation of the effects of relationships between main spatial lower pole calyceal anatomic factors on the success of shock-wave lithotripsy in patients with lower pole kidney stones. Urology 71:801–805

    Article  PubMed  Google Scholar 

  42. Pearle MS, Lingeman JE, Leveillee R, Kuo R, Preminger GM, Nadler RB et al (2005) Prospective, randomized trial comparing shock wave lithotripsy and ureteroscopy for lower pole caliceal calculi 1 cm or less. J Urol 173:2005–2009

    Article  PubMed  Google Scholar 

  43. Danuser H, Muller R, Descoeudres B, Dobry E, Studer UE (2007) Extracorporeal shock wave lithotripsy of lower calyx calculi: how much is treatment outcome influenced by the anatomy of the collecting system? Eur Urol 52:539–546

    Article  PubMed  Google Scholar 

  44. Albala DM, Assimos DG, Clayman RV, Denstedt JD, Grasso M, Gutierrez-Aceves J et al (2001) Lower pole I: a prospective randomized trial of extracorporeal shock wave lithotripsy and percutaneous nephrostolithotomy for lower pole nephrolithiasis-initial results. J Urol 166:2072

    Article  CAS  PubMed  Google Scholar 

  45. Knoll T, Jessen JP, Honeck P, Wendt-Nordahl G (2011) Flexible ureterorenoscopy versus miniaturized PNL for solitary renal calculi of 10-30 mm size. World J Urol 29:755–759

    Article  PubMed  Google Scholar 

  46. Bozkurt OF, Resorlu B, Yildiz Y, Can CE, Unsal A (2011) Retrograde intrarenal surgery versus percutaneous nephrolithotomy in the management of lower-pole renal stones with a diameter of 15 to 20 mm. J Endourol 25:1131–1135

    Article  PubMed  Google Scholar 

  47. Wen CC, Nakada SY (2007) Treatment selection and outcomes: renal calculi. Urol Clin North Am 34:409–419

    Article  PubMed  Google Scholar 

  48. Miller NL, Lingeman JE (2007) Management of kidney stones. BMJ 334:468–472

    Article  PubMed  PubMed Central  Google Scholar 

  49. Schnabel MJ, Gierth M, Brundl J, Chaussy CG, Burger M, Fritsche HM (2014) Antiplatelet and anticoagulative medication during shockwave lithotripsy. J Endourol 28:1034–1039

    Article  PubMed  Google Scholar 

  50. Ohmori K, Matsuda T, Horii Y, Yoshida O (1994) Effects of shock waves on the mouse fetus. J Urol 151:255–258

    CAS  PubMed  Google Scholar 

  51. Carey SW, Streem SB (1992) Extracorporeal shock wave lithotripsy for patients with calcified ipsilateral renal arterial or abdominal aortic aneurysms. J Urol 148:18–20

    CAS  PubMed  Google Scholar 

  52. Schnabel MJ, Gierth M, Chaussy CG, Dotzer K, Burger M, Fritsche HM (2014) Incidence and risk factors of renal hematoma: a prospective study of 1,300 SWL treatments. Urolithiasis 42:247–253

    Article  CAS  PubMed  Google Scholar 

  53. Pace KT, Ghiculete D, Harju M, Honey RJ (2005) Shock wave lithotripsy at 60 or 120 shocks per minute: a randomized, double-blind trial. J Urol 174:595–599

    Article  PubMed  Google Scholar 

  54. Yilmaz E, Batislam E, Basar M, Tuglu D, Mert C, Basar H (2005) Optimal frequency in extracorporeal shock wave lithotripsy: prospective randomized study. Urology 66:1160–1164

    Article  PubMed  Google Scholar 

  55. Madbouly K, El-Tiraifi AM, Seida M, El-Faqih SR, Atassi R, Talic RF (2005) Slow versus fast shock wave lithotripsy rate for urolithiasis: A prospective randomized study. J Urol 173:127–130

    Article  PubMed  Google Scholar 

  56. Ng CF, Lo AK, Lee KW, Wong KT, Chung WY, Gohel D (2012) A prospective, randomized study of the clinical effects of shock wave delivery for unilateral kidney stones: 60 versus 120 shocks per minute. J Urol 188:837–842

    Article  PubMed  Google Scholar 

  57. Ghoneim IA, El-Ghoneimy MN, El-Naggar AE, Hammoud KM, El-Gammal MY, Morsi AA (2010) Extracorporeal shock wave lithotripsy in impacted upper ureteral stones: a prospective randomized comparison between stented and non- stented techniques. Urology 75:45–50

    Article  PubMed  Google Scholar 

  58. Chiong E, Hwee ST, Kay LM, Liang S, Kamaraj R, Esuvaranathan K (2005) Randomized controlled study of mechanical percussion, diuresis, and inversion therapy to assist passage of lower pole renal calculi after shock wave lithotripsy. Urology 65:1070–1074

    Article  PubMed  Google Scholar 

  59. Sayed MAB, El TAM, Aboul EHA, Shaker SE (2001) Steinstrasse after extracorporeal shockwave lithotripsy: Aetiology, prevention and management. BJU Int 88:675–678

    Article  CAS  PubMed  Google Scholar 

  60. Skolarikos A, Alivizatos G, Rosette J de la (2006) Extracorporeal shock wave lithotripsy 25 years later: complications and their prevention. Eur Urol 50:981–990 (discussion 90)

    Article  PubMed  Google Scholar 

  61. Wang M, Shi Q, Wang X, Yang K, Yang R (2011) Prediction of outcome of extracorporeal shock wave lithotripsy in the management of ureteric calculi. Urol Res 39:51–57

    Article  PubMed  Google Scholar 

  62. DasGupta R, Grabe M (2009) Preoperative antibiotics before endourologic surgery: Current recommendations. J Endourol 23:1567–1570

    Article  PubMed  Google Scholar 

  63. Martov A, Gravas S, Etemadian M, Unsal A, Barusso G, D’Addessi A et al (2015) Postoperative infection rates in patients with a negative baseline urine culture undergoing ureteroscopic stone removal: A matched case-control analysis on antibiotic prophylaxis from the CROES URS global study. J Endourol 29:171–180

    Article  PubMed  Google Scholar 

  64. Ramaswamy K, Shah O (2012) Antibiotic prophylaxis after uncomplicated ureteroscopic stone treatment: is there a difference? J Endourol 26:122–125

    Article  PubMed  Google Scholar 

  65. L’Esperance JO, Ekeruo WO, Scales CD Jr, Marguet CG, Springhart WP, Maloney ME et al (2005) Effect of ureteral access sheath on stone-free rates in patients undergoing ureteroscopic management of renal calculi. Urology 66:252–255

    Article  PubMed  Google Scholar 

  66. Stern JM, Yiee J, Park S (2007) Safety and efficacy of ureteral access sheaths. J Endourol 21:119–123

    Article  PubMed  Google Scholar 

  67. Netsch C, Knipper S, Bach T, Herrmann TRW, Gross AJ (2012) Impact of preoperative ureteral stenting on stone-free rates of ureteroscopy for nephroureterolithiasis: A matched-paired analysis of 286 patients, 6. Aufl. Elsevier, New York, S 1214–1219

    Google Scholar 

  68. Rubenstein RA, Zhao LC, Loeb S, Shore DM, Nadler RB (2007) Prestenting improves ureteroscopic stone-free rates. J Endourol 21:1277–1280

    Article  PubMed  Google Scholar 

  69. Song T, Liao B, Zheng S, Wei Q (2012) Meta-analysis of postoperatively stenting or not in patients underwent ureteroscopic lithotripsy. Urol Res 40:67–77

    Article  PubMed  Google Scholar 

  70. Geavlete P, Georgescu D, Nita G, Mirciulescu V, Cauni V (2006) Complications of 2735 retrograde semirigid ureteroscopy procedures: a single-center experience. J Endourol 20:179–185

    Article  PubMed  Google Scholar 

  71. Riley JM, Averch TD (2012) Stone management for the patient on anticoagulation. Curr Urol Rep 13:187–189

    Article  PubMed  Google Scholar 

  72. Bourdoumis A, Stasinou T, Kachrilas S, Papatsoris AG, Buchholz N, Masood J (2014) Thromboprophylaxis and bleeding diathesis in minimally invasive stone surgery. Nat Rev Urol 11:51–58

    Article  CAS  PubMed  Google Scholar 

  73. Leavitt DA, Theckumparampil N, Moreira DM, Elsamra SE, Waingankar N, Hoenig DM et al (2014) Continuing aspirin therapy during percutaneous nephrolithotomy: unsafe or under-utilized? J Endourol 28:1399–1403

    Article  PubMed  Google Scholar 

  74. Sidana A, Patil N, Donovan JF (2012) Role of 1 week of antibiotic prophylaxis before percutaneous nephrolithotomy. Urol Res 40:805–806

    Article  PubMed  Google Scholar 

  75. Tuzel E, Aktepe OC, Akdogan B (2013) Prospective comparative study of two protocols of antibiotic prophylaxis in percutaneous nephrolithotomy. J Endourol 27:172–176

    Article  PubMed  Google Scholar 

  76. Lahme S, Bichler KH, Strohmaier WL, Gotz T (2001) Minimally invasive PCNL in patients with renal pelvic and calyceal stones. Eur Urol 40:619

    Article  CAS  PubMed  Google Scholar 

  77. Desai J, Zeng G, Zhao Z, Zhong W, Chen W, Wu W (2013) A novel technique of ultra-mini-percutaneous nephrolithotomy: introduction and an initial experience for treatment of upper urinary calculi less than 2 cm. Biomed Res Int 2013:490793

    Article  PubMed  PubMed Central  Google Scholar 

  78. Bader MJ, Gratzke C, Seitz M, Sharma R, Stief CG, Desai M (2011) The „all-seeing needle“: initial results of an optical puncture system confirming access in percutaneous nephrolithotomy. Eur Urol

  79. Yamaguchi A, Skolarikos A, Buchholz NP, Chomon GB, Grasso M, Saba P et al (2011) Operating times and bleeding complications in percutaneous nephrolithotomy: a comparison of tract dilation methods in 5,537 patients in the clinical research office of the Endourological Society Percutaneous Nephrolithotomy Global Study. J Endourol 25:933–939

    Article  PubMed  Google Scholar 

  80. Zhong W, Zeng G, Wu W, Chen W, Wu K (2011) Minimally invasive percutaneous nephrolithotomy with multiple mini tracts in a single session in treating staghorn calculi. Urol Res 39:117–122

    Article  PubMed  Google Scholar 

  81. Lahme S, Zimmermanns V, Hochmuth A, Liske P (2008) Stones of the upper urinary tract. Update on minimal-invasive endourological treatment. Arch Ital Urol Androl 80:13–17

    PubMed  Google Scholar 

  82. Salerno A, Nappo SG, Matarazzo E, De Dominicis M, Caione P (2013) Treatment of pediatric renal stones in a western country: A changing pattern, 4. Aufl. W.B. Saunders, Philadelphia, S 835–839

    Google Scholar 

  83. Zeng G, Zhao Z, Wan S, Zhong W, Wu W (2013) Comparison of children versus adults undergoing mini-percutaneous nephrolithotomy: large-scale analysis of a single institution. PLoS ONE 8:e66850

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  84. Antonelli JA, Pearle MS (2013) Advances in Percutaneous Nephrolithotomy, 1. Aufl. W.B. Saunders, Philadelphia, S 99–113

    Google Scholar 

  85. Zhang X, Xia L, Xu T, Wang X, Zhong S, Shen Z (2014) Is the supine position superior to the prone position for percutaneous nephrolithotomy (PCNL)? Urolithiasis 42(1):87–93

    Article  PubMed  Google Scholar 

  86. DasGupta R, Patel A (2013) Percutaneous nephrolithotomy: Does position matter? - Prone, supine and variations, 2. Aufl. Lippincott Williams and Wilkins, London, S 164–168

    Google Scholar 

  87. Zhan HL, Li ZC, Zhou XF, Yang F, Huang JF, Lu MH (2013) Supine lithotomy versus prone position in minimally invasive percutaneous nephrolithotomy for upper urinary tract calculi. Urol Int 91(3):320–325

    Article  PubMed  Google Scholar 

  88. Wang Y, Yao Y, Xu N, Zhang H, Chen Q, Lu Z et al (2013) Prone versus modified supine position in percutaneous nephrolithotomy: A prospective randomized study. Int J Med Sci 10(11):1518–1523

    Article  PubMed  PubMed Central  Google Scholar 

  89. Scoffone CM, Cracco CM, Poggio M, Scarpa RM (2010) Endoscopic combined intrarenal surgery for high burden renal stones. Arch Ital Urol Androl 82:41–42

    PubMed  Google Scholar 

  90. Cracco CM, Scoffone CM, Poggio M, Scarpa RM (2010) The patient position for PNL: does it matter? Arch Ital Urol Androl 82:30–31

    PubMed  Google Scholar 

  91. Scoffone CM, Cracco CM, Cossu M, Grande S, Poggio M, Scarpa RM (2008) Endoscopic combined intrarenal surgery in Galdakao-modified supine Valdivia position: a new standard for percutaneous nephrolithotomy? Eur Urol 54:1393–1403

    Article  PubMed  Google Scholar 

  92. Valdivia JG, Scarpa RM, Duvdevani M, Gross AJ, Nadler RB, Nutahara K et al (2011) Supine versus prone position during percutaneous nephrolithotomy: A report from the Clinical Research Office of the Endourological Society Percutaneous Nephrolithotomy global study. J Endourol

  93. Rosette JJ de la, Tsakiris P, Ferrandino MN, Elsakka AM, Rioja J, Preminger GM (2008) Beyond prone position in percutaneous nephrolithotomy: a comprehensive review. Eur Urol 54:1262–1269

    Article  PubMed  Google Scholar 

  94. Sampaio FJ, Aragao AH (1990) Anatomical relationship between the intrarenal arteries and the kidney collecting system. J Urol 143:679

    CAS  PubMed  Google Scholar 

  95. Sabnis R, Ganpule A, Mishra S, Vyas J, Ganeshmoni R, Jagtap J et al (2014) Exit strategy following MPNL – Prospective randomized study. In: Journal of Urology Conference: 2014 Annual Meeting of the American Urological Association, AUA, Orlando, Conference Start: 20140516 Conference End: 20140521. Bd. 1., S e187

  96. Lu Y, Ping JG, Zhao XJ, Hu LK, Pu JX (2013) Randomized prospective trial of tubeless versus conventional minimally invasive percutaneous nephrolithotomy. World J Urol 31(5):1303–1307

    Article  PubMed  Google Scholar 

  97. Ganesamoni R, Sabnis R, Mishra S, Ganpule A, Vyas J, Jagtap J et al (2013) Randomized controlled trial comparing totally tubeless, tubeless and early tube removal in miniperc. In: Journal of Endourology Conference: 31st World Congress of Endourology and SWL, WCE, New Orleans, Conference Start: 20131022 Conference End: 20131026., S A331

  98. Mishra S, Sabnis RB, Kurien A, Ganpule A, Muthu V, Desai M (2010) Questioning the wisdom of tubeless percutaneous nephrolithotomy (PCNL): a prospective randomized controlled study of early tube removal vs tubeless PCNL. BJU Int

  99. Knoll T, Wezel F, Michel MS, Honeck P, Wendt-Nordahl G (2010) Do patients benefit from miniaturized tubeless percutaneous nephrolithotomy? A comparative prospective study. J Endourol 24:1075–1079

    Article  PubMed  Google Scholar 

  100. Zhong Q, Zheng C, Mo J, Piao Y, Zhou Y, Jiang Q (2013) Total tubeless versus standard percutaneous nephrolithotomy: A meta-analysis, 4. Aufl. Liebert, New Rochelle, S 420–426

    Google Scholar 

  101. Rosette J de la, Assimos D, Desai M, Gutierrez J, Lingeman J, Scarpa R et al (2011) The Clinical Research Office of the Endourological Society Percutaneous Nephrolithotomy Global Study: indications, complications, and outcomes in 5803 patients. J Endourol 25:11–17

    Article  PubMed  Google Scholar 

  102. Preminger GM, Assimos DG, Lingeman JE, Nakada SY, Pearle MS, Wolf JS Jr (2005) Chapter 1: AUA guideline on management of staghorn calculi: diagnosis and treatment recommendations. J Urol 173:1991–2000

    Article  PubMed  Google Scholar 

  103. Akman T, Binbay M, Aslan R, Yuruk E, Ozgor F, Tekinarslan E et al (2012) Long-term outcomes of percutaneous nephrolithotomy in 177 patients with chronic kidney disease: a single center experience. J Urol 187:173–177

    Article  PubMed  Google Scholar 

  104. Okeke Z, Smith AD, Labate G, D’Addessi A, Venkatesh R, Assimos D et al (2012) Prospective comparison of outcomes of percutaneous nephrolithotomy in elderly patients versus younger patients. J Endourol 26:996–1001

    Article  PubMed  Google Scholar 

  105. Gravas S, Montanari E, Geavlete P, Onal B, Skolarikos A, Pearle M et al (2012) Postoperative infection rates in low risk patients undergoing percutaneous nephrolithotomy with and without antibiotic prophylaxis: a matched case control study. J Urol 188:843–847

    Article  PubMed  Google Scholar 

  106. Xue W, Pacik D, Boellaard W, Breda A, Botoca M, Rassweiler J et al (2012) Management of single large nonstaghorn renal stones in the CROES PCNL global study. J Urol 187:1293–1297

    Article  PubMed  Google Scholar 

  107. Seyrek M, Binbay M, Yuruk E, Akman T, Aslan R, Yazici O et al (2012) Perioperative prophylaxis for percutaneous nephrolithotomy: randomized study concerning the drug and dosage. J Endourol 26:1431–1436

    Article  PubMed  Google Scholar 

  108. Tuzel E, Aktepe OC, Akdogan B (2013) Prospective comparative study of two protocols of antibiotic prophylaxis in percutaneous nephrolithotomy. J Endourol. doi:10.1089/end.2012.0331

    PubMed  Google Scholar 

  109. Aron M, Goel R, Gupta NP, Seth A (2005) Incidental detection of purulent fluid in kidney at percutaneous nephrolithotomy for branched renal calculi. J Endourol 19:136–139

    Article  PubMed  Google Scholar 

  110. Akman T, Binbay M, Sari E, Yuruk E, Tepeler A, Akcay M et al (2011) Factors affecting bleeding during percutaneous nephrolithotomy: single surgeon experience. J Endourol 25:327–333

    Article  PubMed  Google Scholar 

  111. Keoghane SR, Cetti RJ, Rogers AE, Walmsley BH (2013) Blood transfusion, embolisation and nephrectomy after percutaneous nephrolithotomy (PCNL, 4. Aufl. Blackwell, Oxford, S 628–632

    Google Scholar 

  112. Heimbach D, Jacobs D, Muller SC, Hesse A (2000) Influence of alkaline solutions on chemolitholysis and lithotripsy of uric acid stones. An in vitro study. Eur Urol 38:621

    Article  CAS  PubMed  Google Scholar 

  113. Soygur T, Akbay A, Kupeli S (2002) Effect of potassium citrate therapy on stone recurrence and residual fragments after shockwave lithotripsy in lower caliceal calcium oxalate urolithiasis: a randomized controlled trial. J Endourol 16:149

    Article  PubMed  Google Scholar 

  114. Lojanapiwat B, Tanthanuch M, Pripathanont C, Ratchanon S, Srinualnad S, Taweemonkongsap T et al (2011) Alkaline citrate reduces stone recurrence and regrowth after shockwave lithotripsy and percutaneous nephrolithotomy. Int Braz J Urol 37:611–616

    Article  CAS  PubMed  Google Scholar 

  115. Mokhless I et al (2012) Tamsulosin for the management of distal ureteral stones in children: a prospective randomized study. [cited 8 101233150] 5:544–548. Available from: http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=medl&NEWS=N&AN=22 099477

  116. Muslumanoglu AY et al (2003) Extracorporeal shock wave lithotripsy as first line treatment alternative for urinary tract stones in children: a large scale retrospective analysis. J Urol 170(6):2405

  117. Knoll T, Schubert AB, Fahlenkamp D, Leusmann DB, Wendt-Nordahl G, Schubert G (2011) Urolithiasis through the ages: data on more than 200,000 urinary stone analyses. J Urol 185:1304–1311

    Article  PubMed  Google Scholar 

  118. Leusmann DB (1991) A classification of urinary calculi with respect to their composition and micromorphology. Scand J Urol Nephrol 25:141

    Article  CAS  PubMed  Google Scholar 

  119. Leusmann DB, Blaschke R, Schmandt W (1990) Results of 5,035 stone analyses: a contribution to epidemiology of urinary stone disease. Scand J Urol Nephrol 24:205

    Article  CAS  PubMed  Google Scholar 

  120. Schubert G, Chudnovskaia MV, Brien G, Tynaliev MT, Popovkin NN, Timin AR (1990) The characteristics of the chemical composition and structure of urinary stones and their prevalence in the cities of Moscow, Berlin and of the Kirghiz SSR. Urol Nefrol (Mosk) 49–54

  121. Türk C, Knoll T, Petric A, Seitz C, Sarica K, Straub M (2016) Guidelines on Urolithiasis. Online http://guidelines.uroweb.org

  122. Pearle MS, Goldfarb DS, Assimos DG, Curhan G, Denu-Ciocca CJ, Matlaga BR et al (2014) Medical management of kidney stones: AUA guideline. J Urol 192(2):316–324

    Article  PubMed  Google Scholar 

  123. Pak CY, Poindexter JR, Adams-Huet B, Pearle MS (2003) Predictive value of kidney stone composition in the detection of metabolic abnormalities. Am J Med 115:26

    Article  CAS  PubMed  Google Scholar 

  124. Hesse A, Kruse R, Geilenkeuser WJ, Schmidt M (2005) Quality control in urinary stone analysis: results of 44 ring trials (1980-2001). Clin Chem Lab Med 43:298–303

    Article  CAS  PubMed  Google Scholar 

  125. Skolarikos A, Straub M, Knoll T, Sarica K, Seitz C, Petrik A et al (2014) Metabolic evaluation and recurrence prevention for urinary stone patients: EAU guidelines. Eur Urol. doi:10.1016/j.eururo.2014.10.029

    PubMed  Google Scholar 

  126. Straub M, Hautmann RE (2006) Evidence-based pharmacological metaphylaxis of stone disease. Urologe A 45:1399–1400 (1402-1405)

    Article  CAS  PubMed  Google Scholar 

  127. Marchini GS, Gebreselassie S, Liu X, Pynadath C, Snyder G, Monga M (2013) Absolute Hounsfield unit measurement on noncontrast computed tomography cannot accurately predict struvite stone composition. J Endourol 27:162–167

    Article  PubMed  Google Scholar 

  128. Zarse CA, McAteer JA, Tann M, Sommer AJ, Kim SC, Paterson RF et al (2004) Helical computed tomography accurately reports urinary stone composition using attenuation values: in vitro verification using high-resolution micro-computed tomography calibrated to fourier transform infrared microspectroscopy. Urology 63:828–833

    Article  PubMed  Google Scholar 

  129. Bellin MF, Renard-Penna R, Conort P, Bissery A, Meric JB, Daudon M et al (2004) Helical CT evaluation of the chemical composition of urinary tract calculi with a discriminant analysis of CT-attenuation values and density. Eur Radiol 14:2134–2140

    Article  PubMed  Google Scholar 

  130. Nayan M, Elkoushy MA, Andonian S (2012) Variations between two 24-hour urine collections in patients presenting to a tertiary stone clinic. Can Urol Assoc J 6:30–33

    Article  PubMed  PubMed Central  Google Scholar 

  131. Parks JH, Goldfisher E, Asplin JR, Coe FL (2002) A single 24-hour urine collection is inadequate for the medical evaluation of nephrolithiasis. J Urol 167:1607–1612

    Article  PubMed  Google Scholar 

  132. Norman RW, Bath SS, Robertson WG, Peacock M (1984) When should patients with symptomatic urinary stone disease be evaluated metabolically? J Urol 132:1137–1139

    CAS  PubMed  Google Scholar 

  133. Laube N, Pullmann M, Hergarten S, Hesse A (2003) Influence of urinary stones on the composition of a 24-hour urine sample. Clin Chem 49:281

    Article  CAS  PubMed  Google Scholar 

  134. Siener R, Hesse A (2003) Fluid intake and epidemiology of urolithiasis. Eur J Clin Nutr 57(Suppl 2):S47–S51

    Article  PubMed  Google Scholar 

  135. Borghi L, Meschi T, Amato F, Novarini A, Romanelli A, Cigala F (1993) Hot occupation and nephrolithiasis. J Urol 150:1757–1760

    CAS  PubMed  Google Scholar 

  136. Fink HA, Akornor JW, Garimella PS, MacDonald R, Cutting A, Rutks IR et al (2009) Diet, fluid, or supplements for secondary prevention of nephrolithiasis: a systematic review and meta-analysis of randomized trials. Eur Urol 56:72–80

    Article  PubMed  PubMed Central  Google Scholar 

  137. Ferraro PM, Taylor EN, Gambaro G, Curhan GC (2013) Soda and other beverages and the risk of kidney stones. Clin J Am Soc Nephrol 8:1389–1395

    Article  PubMed  PubMed Central  Google Scholar 

  138. Hess B, Mauron H, Ackermann D, Jaeger P (1999) Effects of a ’common sense diet’ on urinary composition and supersaturation in patients with idiopathic calcium urolithiasis. Eur Urol 36:136

    Article  CAS  PubMed  Google Scholar 

  139. Borghi L, Schianchi T, Meschi T, Guerra A, Allegri F, Maggiore U et al (2002) Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria. N Engl J Med 346:77–84

    Article  CAS  PubMed  Google Scholar 

  140. Fink HA, Akornor JW, Garimella PS, MacDonald R, Cutting A, Rutks IR et al (2009) Diet, fluid, or supplements for secondary prevention of nephrolithiasis: A systematic review and meta-analysis of randomized trials. Eur Urol 56:72–80

    Article  PubMed  PubMed Central  Google Scholar 

  141. Unruh GE von, Voss S, Sauerbruch T, Hesse A (2004) Dependence of oxalate absorption on the daily calcium intake. J Am Soc Nephrol 15:1567–1573

    Article  CAS  Google Scholar 

  142. Berg W, Bothor C, Pirlich W, Janitzky V (1986) Influence of magnesium on the absorption and excretion of calcium and oxalate ions. Eur Urol 12:274–282

    CAS  PubMed  Google Scholar 

  143. Cochat P, Hulton S‑A, Acquaviva C, Danpure CJ, Daudon M, De Marchi M et al (2012) Primary hyperoxaluria Type 1: indications for screening and guidance for diagnosis and treatment, 5. Aufl. Universite Claude-Bernard Lyon, Lyon, S 1729–1736

    Google Scholar 

  144. Barcelo P, Wuhl O, Servitge E, Rousaud A, Pak CY (1993) Randomized double-blind study of potassium citrate in idiopathic hypocitraturic calcium nephrolithiasis. J Urol 150:1761–1764

    CAS  PubMed  Google Scholar 

  145. Ettinger B, Pak CY, Citron JT, Thomas C, Adams HB, Vangessel A (1997) Potassium-magnesium citrate is an effective prophylaxis against recurrent calcium oxalate nephrolithiasis. J Urol 158:2069–2073

    Article  CAS  PubMed  Google Scholar 

  146. Hofbauer J, Höbarth K, Szabo N, Marberger M (1994) Alkali citrate prophylaxis in idiopathic recurrent calcium oxalate urolithiasis – a prospective randomized study. Br J Urol 73:362–365

    Article  CAS  PubMed  Google Scholar 

  147. Pinheiro VB, Baxmann AC, Tiselius HG, Heilberg IP (2013) The effect of sodium bicarbonate upon urinary citrate excretion in calcium stone formers, 1. Aufl. Elsevier, New York, S 33–37

    Google Scholar 

  148. Brocks P, Dahl C, Wolf H, Transbol I (1981) Do thiazides prevent recurrent idiopathic renal calcium stones? Lancet 2:124–125

    Article  CAS  PubMed  Google Scholar 

  149. Fink HA, Wilt TJ, Eidman KE, Garimella PS, MacDonald R, Rutks IR et al (2012) Medical and dietary therapy for prevention of nephrolithiasis: A systematic review. J Endourol 26:A104–A5

    Google Scholar 

  150. Fink HA, Wilt TJ, Eidman KE, Garimella PS, MacDonald R, Rutks IR et al (2013) Medical management to prevent recurrent nephrolithiasis in adults: A systematic review for an American College of Physicians Clinical Guideline, 7. Aufl. American College of Physicians, Philadelphia, S 535–543

    Google Scholar 

  151. Wolf H, Brocks P, Dahl C (1983) Do thiazides prevent recurrent idiopathic renal calcium oxalate stones? In: Proceedings of the european dialysis and transplant associationeuropean dialysis and transplant association, Bd. 20., S 477–480

    Google Scholar 

  152. Abdulhadi MH, Hall PM, Streem SB (1993) Can citrate therapy prevent nephrolithiasis? Urology 41:221–224

    Article  CAS  PubMed  Google Scholar 

  153. Smith D, Laing C (2013) Importance of citrate and the calcium: citrate ratio in patients with calcium renal lithiasis and severe lithogenesis, BJU Int. doi:10.1111/j.1464-410X.2012.11293.x

  154. Goldfarb DS, MacDonald PA, Gunawardhana L, Chefo S, McLean L (2013) Randomized controlled trial of febuxostat versus allopurinol or placebo in individuals with higher urinary uric acid excretion and calcium stones. Clin J Am Soc Nephrol 8(11):1960–1967

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  155. Khan SR, Shevock PN, Hackett RL (1993) Magnesium oxide administration and prevention of calcium oxalate nephrolithiasis. J Urol 149:412–416

    CAS  PubMed  Google Scholar 

  156. Evan AE, Lingeman JE, Coe FL, Miller NL, Bledsoe SB, Sommer AJ et al (2008) Histopathology and surgical anatomy of patients with primary hyperparathyroidism and calcium phosphate stones. Kidney Int 74:223–229

    Article  CAS  PubMed  Google Scholar 

  157. Mollerup CL, Vestergaard P, Frokjaer VG, Mosekilde L, Christiansen P, Blichert-Toft M (2002) Risk of renal stone events in primary hyperparathyroidism before and after parathyroid surgery: controlled retrospective follow up study. BMJ 325:807

    Article  PubMed  PubMed Central  Google Scholar 

  158. Beck BB, Hoppe B (2006) Is there a genotype-phenotype correlation in primary hyperoxaluria type 1? Kidney Int 70:984–986

    Article  CAS  PubMed  Google Scholar 

  159. Hoppe B, Beck BB, Milliner DS (2009) The primary hyperoxalurias. Kidney Int 75:1264–1271

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  160. Rumsby G (2000) Biochemical and genetic diagnosis of the primary hyperoxalurias: a review. Mol Urol 4(4):349–354

  161. Rumsby G (2005) An overview of the role of genotyping in the diagnosis of the primary hyperoxalurias. Urol Res 33:318–320

    Article  PubMed  Google Scholar 

  162. Takei K, Ito H, Masai M, Kotake T (1998) Oral calcium supplement decreases urinary oxalate excretion in patients with enteric hyperoxaluria. Urol Int 61:192–195

    Article  CAS  PubMed  Google Scholar 

  163. Unruh GE von, Voss S, Sauerbruch T, Hesse A (2003) Reference range for gastrointestinal oxalate absorption measured with a standardized [13C2]oxalate absorption test. JUrol 169:687

    Google Scholar 

  164. Hesse AT, Tiselius H‑G, Siener R (2009) Urinary Stones, Diagnosis, Treatment and Prevention of Recurrence, 3. Aufl. Karger, Basel

    Book  Google Scholar 

  165. Domrongkitchaiporn S, Khositseth S, Stitchantrakul W, Tapaneya OW, Radinahamed P (2002) Dosage of potassium citrate in the correction of urinary abnormalities in pediatric distal renal tubular acidosis patients. Am J Kidney Dis 39:383–391

    Article  CAS  PubMed  Google Scholar 

  166. Scholz D, Schwille PO, Sigel A (1982) Double-blind study with thiazide in recurrent calcium lithiasis. J Urol 128:903–907

    CAS  PubMed  Google Scholar 

  167. Mattle D, Hess B (2005) Preventive treatment of nephrolithiasis with alkali citrate – a critical review. Urol Res 33:73–79

    Article  CAS  PubMed  Google Scholar 

  168. Shekarriz B, Stoller ML (2002) Uric acid nephrolithiasis: current concepts and controversies. J Urol 168:1307–1314

    Article  CAS  PubMed  Google Scholar 

  169. Goldfarb DS, MacDonald PA, Gunawardhana L, Chefo S, McLean L (2013) Randomized controlled trial of febuxostat versus allopurinol or placebo in individuals with higher urinary uric acid excretion and calcium stones. Clin J Am Soc Nephrol. doi:10.2215/CJN.01760213

  170. Gettman MT, Segura JW (1999) Struvite stones: diagnosis and current treatment concepts. J Endourol 13:653–658

    Article  CAS  PubMed  Google Scholar 

  171. Eswara JR, Shariftabrizi A, Sacco D (2013) Positive stone culture is associated with a higher rate of sepsis after endourological procedures. Urolithiasis 41:411–414

    Article  CAS  PubMed  Google Scholar 

  172. Hesse A, Heimbach D (1999) Causes of phosphate stone formation and the importance of metaphylaxis by urinary acidification: a review. World J Urol 17:308

    Article  CAS  PubMed  Google Scholar 

  173. Williams JJ, Rodman JS, Peterson CM (1984) A randomized double-blind study of acetohydroxamic acid in struvite nephrolithiasis. N Engl J Med 311:760–764

    Article  CAS  PubMed  Google Scholar 

  174. Knoll T, Zollner A, Wendt-Nordahl G, Michel MS, Alken P (2005) Cystinuria in childhood and adolescence: recommendations for diagnosis, treatment, and follow-up. Pediatr Nephrol 20:19–24

    Article  PubMed  Google Scholar 

  175. Barbey F, Joly D, Rieu P, Mejean A, Daudon M, Jungers P (2000) Medical treatment of cystinuria: critical reappraisal of long-term results. J Urol 163:1419

    Article  CAS  PubMed  Google Scholar 

  176. Pak CY, Fuller C, Sakhaee K, Zerwekh JE, Adams BV (1986) Management of cystine nephrolithiasis with alpha-mercaptopropionylglycine. J Uro 136:1003

    CAS  Google Scholar 

  177. Birwe H, Schneeberger W, Hesse A (1991) Investigations of the efficacy of ascorbic acid therapy in cystinuria. Urol Res 19:199

    Article  CAS  PubMed  Google Scholar 

  178. Cohen TD, Streem SB, Hall P (1995) Clinical effect of captopril on the formation and growth of cystine calculi. J Urol 154:164

    Article  CAS  PubMed  Google Scholar 

  179. Coulthard MG, Richardson J, Fleetwood A (1995) The treatment of cystinuria with captopril. Am J Kidney Dis 25:661

    Article  CAS  PubMed  Google Scholar 

  180. Pais VM Jr, Lowe G, Lallas CD, Preminger GM, Assimos DG (2006) Xanthine urolithiasis. Urology 67:1084 e9–1084 11

    Article  PubMed  Google Scholar 

  181. Allen TD, Spence HM (1966) Matrix stones. J Urol 95:284–290

    CAS  PubMed  Google Scholar 

  182. Bani-Hani AH, Segura JW, Leroy AJ (2005) Urinary matrix calculi: our experience at a single institution. J Urol 173:120–123

    Article  PubMed  Google Scholar 

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  1. Urologische Klinik Sindelfingen, Klinikum Sindelfingen-Böblingen, Arthur-Gruber-Str. 70, 71065, Sindelfingen, Deutschland

    T. Knoll & G. Wendt-Nordahl

  2. Urologisches Zentrum Hamburg, Asklepios Klinikum Harburg, Hamburg, Deutschland

    T. Bach

  3. Klinik für Urologie, Klinikum Stuttgart, Stuttgart, Deutschland

    U. Humke

  4. Klinik für Urologie, Universitätsmedizin Mainz, Mainz, Deutschland

    A. Neisius

  5. Klinik für Urologie, Universitätsmedizin Mannheim, Mannheim, Deutschland

    R. Stein

  6. Klinik für Urologie, Universitätsklinikum Freiburg, Freiburg, Deutschland

    M. Schönthaler

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T. Knoll, T. Bach, U. Humke, A. Neisius, R. Stein, M. Schönthaler und G. Wendt-Nordahl geben an, dass kein Interessenkonflikt besteht.

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Knoll, T., Bach, T., Humke, U. et al. S2k-Leitlinie zur Diagnostik, Therapie und Metaphylaxe der Urolithiasis (AWMF 043/025). Urologe 55, 904–922 (2016). https://doi.org/10.1007/s00120-016-0133-2

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