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Dabigatran oder Warfarin für Patienten mit mechanischem Herzklappenersatz

RE-ALIGN (Randomized, Phase II Study to Evaluate the Safety and Pharmacokinetics of Oral Dabigatran Etexilate in Patients after Heart Valve Replacement)

Dabigatran or warfarin for patients with mechanical heart valves

RE-ALIGN (Randomized, Phase II Study to Evaluate the Safety and Pharmacokinetics of Oral Dabigatran Etexilate in Patients after Heart Valve Replacement)

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Literatur

  1. Camm JA, Lip GYH, De Caterina R et al (2012) 2012 focused update of the ESC guidelines for the management of atrial fibrillation. Eur Heart J 33:2719–2747

    Google Scholar 

  2. Hylek EM (2013) Dabigatran and mechanical heart valves – not as easy as we hoped. N Engl J Med 369:1264–1266

  3. Maegdefessel L, Linde T, Krapiec F et al (2010) In vitro comparison of dabigatran, unfractionated heparin, and low-molecular-weight heparin in preventing thrombus formation on mechanical heart valves. Thromb Res 126:e196–e200

    Article  CAS  PubMed  Google Scholar 

  4. Sun JCJ, Davidson MJ, Lamy A, Eikelboom JW (2009) Antithrombotic management of patients with prosthetic heart valves: current evidence and future trends. Lancet 374:565–576

    Article  PubMed  Google Scholar 

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Einhaltung ethischer Richtlinien

Interessenkonflikt. T. Zeus, S. Nitschmann und M. Kelm geben an, dass kein Interessenkonflikt besteht. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.

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Zeus, T., Nitschmann, S. & Kelm, M. Dabigatran oder Warfarin für Patienten mit mechanischem Herzklappenersatz. Internist 55, 1108–1111 (2014). https://doi.org/10.1007/s00108-014-3559-x

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  • DOI: https://doi.org/10.1007/s00108-014-3559-x

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