Summary
A series of imaging features of extranodal, multi-systemic involvements in Non-Hodgkin’s lymphoma (NHL) were investigated. The clinical data and imaging findings of 16 patients with pathologically proved NHL were retrospectively analyzed. The related literatures were reviewed. Of the 16 cases of NHL, skeletal involvement was found in 4, nasal cavity and nasal sinuses were involved in 4, too. Lesion in the thorax was seen in 3 patients, hepatic involvement occurred in one case, cerebral ventricle was affected in 3 cases, mesentery was involved in one case. Even though extranodal involvement of NHL exhibited extremely variable patterns, there were some relatively typical imaging findings. Emphasized in this report were the relatively specific imaging manifestations of different systems, which may mimic infectious or other neoplasms of different sites. The importance of imaging studies lies in the availability for diagnosis, staging and follow-up of NHL. Combined with the clinical and other related information, the diagnostic accuracy can be further improved, thus, providing reliable evidence in guiding clinical management.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Sandrasegaran K, Robinson P J, Selby P. Review: Staging of lymphoma in adults. Clin Radiol, 1994, 49: 149
Scutellari P N, Borgatti L, Spanedda R. Non-hodgkin’s lymphomas of extranodal localization. Strategies for imaging diagnosis. Radiol Med (Torino), 2000, 100 (4):262
Malms J, Engelbrecht V, Zahner Jet al. Radiologic diagnosis of primary extranodal lymphoma manifestations. Radiologe, 1997, 37(1):27
Spagnoli M D, Gattoni F, Viganotti G. Roentgenographic aspects of non-Hodgkin’s lymphoma presenting with osseous lesions. Skeletal Radiol, 1982, 8:39
Edeiken-Monroe B, Edeiken J, Kim E E. Radiologic concepts of lymphoma of bone. Radiol Clin North Am, 1990, 28:841
Clayton F, Butler J J, Ayala A Get al. Non-Hodgkin’s lymphoma of bone: pathologic and radiologic features with clinical correlates. Cancer, 1990, 60:2494
White L M, Siegel S, Shin S Set al. Primary lymphoma of the calcaneous. Skeletal Radiol, 1996, 25:775
Nakamura K, Uehara S, Omagari Jet al. Primary Non-Hodgkin lymphoma of the sinonasal cavities: correlation of CT evaluation with clinical outcome. Radiology, 1997, 204:431
Yasumoto M, Taura S, Shibuya Het al. Primary malignant lymphoma of the maxillary sinus: CT and MRI. Neuroradiology, 2000, 42:285
Virginia A U, Lenung A N. Radiologic manifestation of lymphoma in the thorax. AJR Am J Roentgenol, 1997, 168:93
Boger-Megiddo I, Apter S, Spencer J Aet al. Is chest CT sufficient for follow-up of primary mediastinal B-cell lymphoma in remission?. AJR Am J Roentgenol, 2002, 178:165
Chou C K, Chen L T, Sheu R Set al. MRI Manifestations of Gastrointestinal lymphoma. Abdom Imaging, 1994, 19:495
Schweiger F, Shinder R, Rubin S. Primary lymphoma of the liver: A case report and review. Can J Gastroenterol, 2000, 14:955
Maher M M, McDermott S R, Fenlon H Met al. Imaging of primary non-Hodgkin’s lymphoma of the liver. Clin Radiol, 2001, 56(4):295
Roman-Goldstein S M, Golman, D L, Howieson Jet al. MR of primary CNS lymphoma in immunologically normal patients. AJNR, 1992, 13:1207
Ambinder R F, Sparano J A. Primary central nervous system lymphoma. Cancer Treat Res, 2001, 104:231
Author information
Authors and Affiliations
Additional information
ZHANG Jingfeng, male, born in 1973 Resident
Rights and permissions
About this article
Cite this article
Jingfeng, Z., Renfa, W., Yonggang, L. et al. Extranodal imaging manifestations of Non-Hodgkin’s lymphoma. Current Medical Science 23, 324–327 (2003). https://doi.org/10.1007/BF02829528
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02829528