Total synthesis ofdl-9(11)-dehydrotestosterone anddl-testosterone

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access


17β-Hydroxy-des-A-androst-9-en-5-one (II, R=OH), prepared fromtrans-1β-hydroxy-8-methyl-4, 5-(3′-methyl-4′-methoxybenzo)-hydrindane (I, R=CH3)′, has been converted intodl-9(II)-dehydrotestosterone (IV, R=OH) anddl-testosterone (IX) in very short sequences of steps, albeit in poor yields.

Presented at the 8th International Symposium on the Chemistry of Natural Products, New Delhi, February 1972, 223.