Resume
De nombreux virus ont été détectés dans le sperme et sont par conséquent susceptibles d'être transmis au cours des actes d'Assistance Médicale à la Procréation (AMP). Le risque de contamination en AMP concerne la mère et l'enfant conçu, mais également les autres couples et le personnel technique manipulant les gamètes. Il pose un triple problème: de santé publique, éthique et juridique. Après un bref rappel des mesures de sécurité sanitaire en vigueur, ces différents points seront abordés au travers de 3 exemples = le cytomégalovirus (CMV), les virus des hépatites B (VHB), C (VHC) et G (VHG), et le virus de l'immunodéficience humaine (VIH).
Abstract
Detection of virus (VIH, CMV, HSV, HPV, HCV, HBV) in semen raises the issue of the risk of transmission of infection to the mother and the future baby, to other gametes and embryos in the incubator, and to technicians related to the manipulation of contaminated biological fluids in the standard IVF laboratory. The transmissibility of virus through medical techniques is a critical question in public health care. For each virus, it becomes essential to assess transmission risk in ART, especially inin vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI), to define the management of couples according to their viral status. Here, we studied different virus: CMV, HCV, HBV and HIV and proposed practical attitudes towards virus screening and management in infertility centers.
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