Article

The Journal of Nutrition Health and Aging

, Volume 12, Issue 7, pp 433-450

Sarcopenia: Its assessment, etiology, pathogenesis, consequences and future perspectives

  • Y. RollandAffiliated withInserm, U558University of Toulouse IIIDepartment of Geriatric Medicine, CHU Toulouse Email author 
  • , S. CzerwinskiAffiliated withDepartment of Community Health, Lifespan Health Research Center, Boonshoft School of Medicine, Wright State University Dayton
  • , G. Abellan van KanAffiliated withDepartment of Geriatric Medicine, CHU Toulouse
  • , J. E. MorleyAffiliated withGeriatric Research, Education and Clinical CenterMedical Center, and Division of Geriatric Medicine, Saint Louis University
  • , M. CesariAffiliated withDepartment of Aging and Geriatric Research, University of Florida - Institute on Aging
  • , G. OnderAffiliated withDepartment of Gerontological, Geriatric and Physiatric Sciences, Catholic University of Sacred Heart
  • , J. WooAffiliated withInserm, U558Division of geriatrics, Department of Medicine and Therapeutics. The Prince of Wales Hospital, Chinese University of Hong-Kong
  • , R. BaumgartnerAffiliated withInserm, U558Department of Epidemiology and Population Health, School of Public Health and Information Sciences, University of Louisville
  • , F. PillardAffiliated withInserm, U558Service d’Exploration de la Fonction Respiratoire et de Medecine du Sport, Hôpital Larrey
    • , Y. BoirieAffiliated withInserm, U558UFR Médecine, UMR1019, Unité Nutrition Humaine, University Clermont 1Clinical Nutrition Unit, CHU Clermont-Ferrand
    • , W. M. C. ChumleaAffiliated withDepartment of Community Health, Lifespan Health Research Center, Boonshoft School of Medicine, Wright State University Dayton
    • , B. VellasAffiliated withInserm, U558University of Toulouse IIIDepartment of Geriatric Medicine, CHU Toulouse

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access

Abstract

Sarcopenia is a loss of muscle protein mass and loss of muscle function. It occurs with increasing age, being a major component in the development of frailty. Current knowledge on its assessment, etiology, pathogenesis, consequences and future perspectives are reported in the present review. On-going and future clinical trials on sarcopenia may radically change our preventive and therapeutic approaches of mobility disability in older people.