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Environmental fate and bioavailability of agent orange and its associated dioxin during the vietnam war

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Abstract

Background

In 1996, the Committee on the Assessment of Wartime Exposure to Herbicides in Vietnam of the National Academy of Sciences’ Institute of Medicine (IOM) issued a report on an exposure model for use in epidemiological studies of Vietnam veterans. This exposure model would consider troop locations based on military records; aerial spray mission data; estimated ground spraying activity; estimated exposure opportunity factors; military indications for herbicide use; and considerations of the composition and environmental fate of herbicides, including changes in the TCDD content of the herbicides over time, the persistence of TCDD and herbicides in the environment, and the degree of likely penetration of the herbicides into the ground. When the final report of the IOM Committee was released in October 2003, several components of the exposure model envisioned by the Committee were not addressed. These components included the environmental fate of the herbicides, including changes in the TCDD content over time, the persistence of TCDD and herbicides in the environment, and the degree of likely penetration of herbicides into the ground. This paper is intended to help investigators understand better the fate and transport of herbicides and TCDD from spray missions, particularly in performing epidemiological studies.

Methods

This paper reviews the published scientific literature related to the environmental fate of Agent Orange and the contaminant, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), and discusses how this affected the potential exposure to TCDD of ground troops in Vietnam. Specifically, the mechanisms of dissipation and degradation as they relate to environmental distribution and bioavailability are addressed.

Results

The evaluation of the spray systems used to disseminate herbicides in Vietnam showed that they were capable of highly precise applications both in terms of concentrations sprayed and area treated. Research on tropical forest canopies with leaf area indices (a measure of foliage density) from 2 to 5 indicated that the amount of herbicide and associated TCDD reaching the forest floor would have been between 1 and 6% of the total aerial spray. Studies of the properties of plant surface waxes of the cuticle layer suggested that Agent Orange, including the TCDD, would have dried (i.e., be absorbed into the wax layer of the plant cuticle) upon spraying within minutes and could not be physically dislodged. Studies of Agent Orange and the associated TCDD on both leaf and soil surface have demonstrated that photolysis by sunlight would have rapidly decreased the concentration of TCDD, and this process continued in shade. Studies of ‘dislodgeable foliar residues’ (DFR, the fraction of a substance that is available for cutaneous uptake from the plant leaves) showed that only 8% of the DFR was present 1 hr after application. This dropped to 1% of the total 24 hrs after application. Studies with human volunteers confirmed that after 2 hrs of saturated contact with bare skin, only 0.15–0.46% of 2,4,5-T, one of the phenoxy acetic acid compounds that was an active ingredient of Agent Orange, entered the body and was eliminated in the urine.

Conclusions

The prospect of exposure to TCDD from Agent Orange in ground troops in Vietnam seems unlikely in light of the environmental dissipation of TCDD, little bioavailability, and the properties of the herbicides and circumstances of application that occurred. Photochemical degradation of TCDD and limited bioavailability of any residual TCDD present in soil or on vegetation suggest that dioxin concentrations in ground troops who served in Vietnam would have been small and indistinguishable from background levels even if they had been in recently treated areas. Laboratory and field data reported in the literature provide compelling evidence on the fate and dislodge-ability of herbicide and TCDD in the environment. This evidence of the environmental fate and poor bioavailability of TCDD from Agent Orange is consistent with the observation of little or no exposure in the veterans who served in Vietnam. Appreciable accumulation of TCDD in veterans would have required repeated long-term direct skin contact of the type experienced by United States (US) Air Force RANCH HAND and US Army Chemical Corps personnel who handled or otherwise had direct contact with liquid herbicide, not from incidental exposure under field conditions where Agent Orange had been sprayed.

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References

  1. Institute of Medicine (1997): Characterizing Exposure of Veterans to Agent Orange and Other Herbicides Used in Vietnam: Scientific Considerations Regarding a Request for Proposals for Research. National Academy Press, Washington, DC

    Google Scholar 

  2. Institute of Medicine (2003): Characterizing Exposure of Veterans to Agent Orange and Other Herbicides Used in Vietnam. National Academy Press, Washington, DC

    Google Scholar 

  3. Irish KR, Darrow RA, Minarik CE (1969): Information Manual for Vegetation Control in Southeast Asia. Miscellaneous Publication 33, Plant Science Laboratories, Department of the Army, Frederick, MD http://www.nal.usda.gov/speccoll/findaids/agentorange/text/00073.pdf

    Google Scholar 

  4. Young AL, Newton M (2004): Long Overlooked Historical Information on Agent Orange and TCDD Following Massive Applications of 2,4,5-T-Containing Herbicides, Eglin Air Force Base, Florida. ESPR - Environ Sci & Pollut Res 11 (4) 209–221

    Article  Google Scholar 

  5. Flynn CL (1964): Development Test of the Internal Defoliant Dispenser, A/A 45Y-1. Deputy Test Operations, Air Proving Ground Center, Air Forces Systems Command, US Air Force, Eglin AFB, FL http://www.nal.usda.gov/speccoll/findaids/agentorange/text/00346.pdf

    Google Scholar 

  6. Klein RE, Harrigan ET (1969): Comparison Test of Defoliants. Technical Report ADTC-TR-30, Vol I and II, Directorate of Test and Evaluation, Armament Development and Test Center, Eglin AFB, FL hrtp://www.nal.usda.gov/speccoll/finaids/agentorange/text/0003 l.pdf

    Google Scholar 

  7. Buckingham, WA (1982): The Air Force and Herbicides in Southeast Asia, 1961–1971. Office of Air Force History, Washington, DC

    Google Scholar 

  8. Cecil PF (1986): Herbicidal Warfare: The RANCH HAND Project in Vietnam. Praeger Special Studies, Praeger Scientific, New York, NY

    Google Scholar 

  9. 504th Tactical Air Support Group (1969): Standards/Evaluation and Information Files for FACs. Pacific Air Command, April 1969

  10. Young AL, Cecil PF, Guilmartin JF (2004): Assessing Possible Exposures of Ground Troops to Agent Orange During the Vietnam War: The Use of Contemporary Military Records. ESPR - Environ Sci & Pollut Res 11 (6) 349–358 http://dx.doi.org/l0.1065/espr2004.10.221

    CAS  Google Scholar 

  11. Harrigan ET (1970): Calibration Test of the UC-123K/A/A 45Y-1 Spray System. Technical Report ADTC-TR-70-36, Armament Development and Test Center, Eglin AFB, FL http://www.nal.usda.gov/speccoll/findaids/agentorange/text/00371.pdf

    Google Scholar 

  12. Data Management Agency (1970): Command Manual for Herbicide Report System (HERBS). Chemical Operations Division, Military Assistance Command Vietnam, Document No. DAR U07, 30 June 1970. NTIS AD8759442

  13. Yates WE, Akesson NB, Cowden RE (1978): Atmospheric Transport of Sprays from Helicopter Applications in Mountainous Terrain. Paper #78–1504, IN Am Soc Agric Engineers Meeting, December 18–20, 1978

  14. Taconi NE, Jones JM (1970): Methods for Predicting Contamination Density and Off-Target Drift of Defoliant Materials. Technical Report, AFATL-TR-70-26, Air Force Armament Laboratory, Air Force Systems Command, Eglin AFB, FL http://www.nal.usda.gov/speccoll/findaids/agentorange/text/00075.pdf

    Google Scholar 

  15. Yates WE, Akesson NB, Cowden RE (1984): Measurements of Drop Size Frequency from Nozzles Used for Aerial Applications of Pesticides in Forests. Final Report, USDA Forest Service Equipment Development Center, Missoula, MT

    Google Scholar 

  16. Stellman JM, Stellman SD, Christian R, Weber R, Tomasallo C (2003): The Extent and Patterns of Usage of Agent Orange and Other Herbicides in Vietnam. Nature 422, 681–687

    Article  CAS  Google Scholar 

  17. Newton M, Norris LA (1981): Potential Exposure of Humans to 2,4,5-T and TCDD in Oregon Coast Range. Fund Appl Toxicol 1, 339–346

    Article  CAS  Google Scholar 

  18. Lavy TL, Shepard JS, Mattice JD (1980): Exposure Measurements of Applicators Spraying 2,4,5-Trichlorophenoxyacetic acid in Forests. J Agric Food Chem 28, 626–630

    Article  CAS  Google Scholar 

  19. Lavy TL (1987): Human Exposure to Phenoxy Herbicides. Monograph published by the Agent Orange Projects Office, Department of Medicine and Surgery, Veterans Administration, Washington, DC

    Google Scholar 

  20. Newton M, Homer LM, Cowell JE, White DE, Cole EC (1994): Dissipation of Glyphosphate and Amino-methylphosphonic acid in North American Forests. J Agric Food Chem 42, 1795–1802

    Article  CAS  Google Scholar 

  21. Smith LS, Smith TM (1998): Elements of Ecology. The Benjamin Cummings Publishing Company, Inc., Menlo Park, CA

    Google Scholar 

  22. Tschirley FH (1968): Response of Tropical and Subtropical Woody Plants to Chemical Treatment. Technical Report CR-13-67, Agricultural Research Service, US Department of Agriculture, Washington, DC

    Google Scholar 

  23. NRC (1974): The Effects of Herbicides in South Vietnam. Part A. Summary and Conclusions. Committee on the Effects of Herbicides in South Vietnam, National Research Council, National Academy of Sciences, Washington, DC http://www.nal.usda.gov/speccoll/findaids/agentorange/text/00181.pdf

    Google Scholar 

  24. Loss MA (1975): Phenoxyalkanoic Acid. Chapter 1: 1–28. In: Kearney PC, Kaufman DD (eds), Herbicides: Chemistry, Degradation, and Mode of Action, Marcel Dekker, Inc., New York, NY

    Google Scholar 

  25. McConnell AF (1970): Mission: RANCH HAND. Air University Review 21 (3) 89–94 http://www.nal.usda.gov/speccoll/findaids/agentorange/text/00159.pdf

    Google Scholar 

  26. ESG (1986): Services HERB Tape - A Record of Helicopter and Ground Spraying Missions, Aborts, Leaks, and Incidents. US Army and Joint Services Environmental Support Group (ESG), Washington, DC http://www.nnl.usda.gov/speccoll/findaids/agentoranpe/text/00185.pdf

    Google Scholar 

  27. Horan RA (1965): Evaluation of Emergency Dump Valve Modification to Internal Defoliant Dispenser A/A 45Y-1. Technical Report, Air Proving Ground Center, Air Force Systems Command, US Air Force, Eglin AFB, FL http://www.nal.usda.gov/speccoll/findaids/agentoranpe/text/00355.pdf

    Google Scholar 

  28. Blackman GE, Fryer JD, Lang A, Newton M (1974): Persistence and Disappearance of Herbicides in Tropical Soils. Part B. Working Papers on the Effects of Herbicides in South Vietnam, Committee on Effects of Herbicides in South Vietnam, National Research Council, National Academy of Sciences, Washington, DC http://www.nal.usda.gov/speccoll/findaids/agentorange/text/00092.pdf

    Google Scholar 

  29. Young AL (1974): Ecological Studies on a Herbicide-Equipment Test Area (Test Area C-52A), Eglin AFB Reservation, Florida. Technical Report AFATL-TR-74-12, Air Force Armament Laboratory, Air Force Systems Command, Eglin AFB, FL http://www.nal.usda.gov/speccoll/findaids/agentorange/text/03809.pdf

    Google Scholar 

  30. Schecter A, Dai LC, Papke O, Prange J, Constable J, Matsuda M, Thao VD, Piskac A (2001): Dioxin Levels in Vietnamese People, Food and Environmental Samples: Evidence of Current Contamination with 2,3,7,8-TCDD from Agent Orange Sprayed Over 30 Years Ago. Organohalogen Compounds 52, 156–160

    CAS  Google Scholar 

  31. Papke O, Furst P, Malisch R, Ryan JJ, Schecter A (2003): Dioxins in Vietnamese and in Vietnamese Environment: Early and Recent Investigations. Organohalogen Compounds 64, 227–230

    Google Scholar 

  32. Young AL, Regens JL (2004): Procurement Records and Dioxin Levels for Herbicides Used in the Vietnam War (in preparation)

  33. Young AL, Thalken CE, Cairney WJ (1979): Herbicide Orange Site Treatment and Environmental Monitoring: Summary and Recommendations for Naval Construction Battalion Center, Gulfport, Mississippi. Technical Report OEHL-TR-79-169, USAF Occupational and Environmental Health Laboratory, Aerospace Medical Division, Brooks AFB, TX

    Google Scholar 

  34. Channell RE, Stoddart TL (1984): Herbicide Orange Monitoring Program. Technical Report ESL-TR-83-56, Engineering & Services Laboratory, Air Force Engineering & Services Center Tyndall AFB, FL

    Google Scholar 

  35. Young AL, Cairney WJ, Thalken CE (1983): Persistence, Movement, and Decontamination Studies of TCDD in Storage Sites Massively Contaminated with Phenoxy Herbicides. Chemosphere 12 (4/5) 713–716

    Article  CAS  Google Scholar 

  36. Crockett AB, Propp A, Kimes T (1987): Herbicide Orange Site Characterization Study, Naval Construction Battalion Center. Technical Report ESL-TR-86-21, Final Report April 1984-September 1986. Engineering & Services Laboratory, Air Force Engineering & Services Center, Tyndall AFB, FL

    Google Scholar 

  37. Young AL (1983): Long-Term Studies on the Persistence and Movement of TCDD in a Natural Ecosystem. Environ Sci Res 26: 173–190

    CAS  Google Scholar 

  38. Crosby DG, Wong AS (1973): Photodecomposition of 2,4,5-Tri-chlorophenoxyacetic Acid (2,4,5-T) in Water. J Agric Food Chem 21, 1052–1054

    Article  CAS  Google Scholar 

  39. Crosby DG, Moilanen KW, Wong AS (1973): Environmental Generation and Degradation of Dibenzodioxins and Dibenzofurans. Environ Health Perspect 5, 259–266

    Article  CAS  Google Scholar 

  40. Crosby DG, Wong AS (1977): Environmental Degradation of 2,3,7,8-Tetrachiorodibenzo-p-dioxin (TCDD). Science 195, 1337–1338

    Article  CAS  Google Scholar 

  41. Crosby DG (1978): Conquering the Monster - the Photochemical Destruction of Chlorodioxins. Adv Chem Ser 73, 1–12

    CAS  Google Scholar 

  42. Wong AS, Crosby DG (1978): Decontamination of 2,3,7,8-Tetra-chlorodibenzo-p-dioxin (TCDD) by Photochemical Action. SP Medical & Scientific Books, New York, NY

    Google Scholar 

  43. Crosby DG (1983): Methods of Photochemical Degradation of Halogenated Dioxins in View of Environmental Reclamation. In: Couston F, Pocciari F (eds), Accidental Exposure to Dioxins, Human Health Aspects. Academic Press, 149–161

  44. Bentson KP (1989): Short-term Fate of Xenobiotic Substances in Pesticide Deposits. Ph.D. Dissertation, Oregon State University College of Forestry, Corvallis, OR

    Google Scholar 

  45. Schuler F, Schmid P, Schlatter C (1998): Photodegradation of Poly-chlorinatted Dibenzo-p-dioxins and Dibenzofurans in Cuticular Waxes of Laurel Cherry (Prunus laurocerasus). Chemosphere 36, 21–34

    Article  CAS  Google Scholar 

  46. Konstantinov AD (1999): Photochemical Reaction of Chloroaro-matic Compounds. Ph.D. Dissertation, University of Guelph, Guelph, Canada

    Google Scholar 

  47. Konstantinov AD, Johnston AM, Cox BJ, Petrulis JR, Orzechowski, MT, Bunce NJ (2000): Photolytic Method for Destruction of Dioxins in Liquid Laboratory Waste and Identification of Photoprod-ucts from 2,3,7,8-TCDD. Environ Sci Technol 34, 143–148

    Article  CAS  Google Scholar 

  48. Crafts AS (1956): The Mechanisms of Translocation: Methods of Study with C14 labeled 2,4-D. Hilgardia 26, 287–306

    CAS  Google Scholar 

  49. McKay D, Shiu WY, Ma KC (1992): Illustrated Handbook of Physical-Chemical Properties and Environmental Fate for Organic Chemicals (Polynuclear Aromatic Hydrocarbons, Polychlorinated Dioxins and Dibenzofurans). Lewis Publishers, MI

    Google Scholar 

  50. Travis CC, Hattemer-Frey HA (1987): Human Exposure to 2,3,7,8-TCDD. Chemosphere 16, 2331–2342

    Article  CAS  Google Scholar 

  51. Buser HR (1988): Rapid Photolytic Decomposition of Brominated and Brominated/Chlorinated Dibenzodioxins and Dibenzofurans. Chemophere 17, 889–903

    Article  CAS  Google Scholar 

  52. Atkinson R (1987): Estimation of OH Radical Reaction Rate Constants and Atmospheric Lifetimes for Polychlorobiphenyls, Dibenzo-p-dioxins, and Dibenzofurans. Environ Sci Technol 21 (3) 305–307

    Article  CAS  Google Scholar 

  53. Jensen DJ, Getzendaner ME, Hummel RA, Turley J (1983): Residue Studies for 2,4,5-Trichlorophenoxy Acetic Acid and 23,7,8-Tetrachloro-dibenzo-p-dioxin in Grass and Rice. J Agric Food Chem 31, 118–122

    Article  CAS  Google Scholar 

  54. Noms LA (1996): Degradation of 2,4-D and 2,4,5-T in Forest Litter. J Forestry 94, 475–477

    Google Scholar 

  55. Freeman RA, Schroy JM (1989): Comparison of the Rate of TCDD Transport at Times Beach and at Eglin AFB. Chemosphere 18 (1–6) 1305–1312

    Article  Google Scholar 

  56. Matsumura FA, Benezet HJ (1973): Studies on the Bioaccumulation and Microbial Degradation of 2,3,7,8-Tetrachlorodibenzo-p-di-oxin. Environ Health Perspect 81, 253–258

    Article  Google Scholar 

  57. Plimmen JR (1978): Photolysis of TCDD and Trifluralin on Silica and Soil. Bull Environ Contam Toxicol 20 (1) 87–92

    Article  Google Scholar 

  58. Podoll RT, Jaber Hm, Mill T (1986): Tetrachlorodibenzodioxin: Rates of Volatilization and Photolysis in the Environment. Environ Sci Technol 20 (5) 490–492

    Article  CAS  Google Scholar 

  59. Anderson YB, Jackson JA, Birnbaum LS (1993): Maturational changes in dermal absorption of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in Fischer 344 rats. Toxicol Appl Pharmacol 119 (2) 214–20

    Article  CAS  Google Scholar 

  60. Poiger H, Schlatter C (1980): Influence of solvents and absorbents on dermal and intestinal absorption of TCDD. Food Cosmet Toxicol 18 (5) 477–481

    Article  CAS  Google Scholar 

  61. Aprea C, Centi L, Lunghini L, Banchi B, Forti MA, Sciarra G (2002): Evaluation of Respiratory and Cutaneous Doses of Chlorothalonil During Re-entry in Greenhouses. J Chromatogr B Analyt Technol Biomed Life Sci 778 (1–2) 131–145

    Article  CAS  Google Scholar 

  62. Harris SA, Solomon KR (1992): Percutaneous Penetration of 2,4-Dichlorophenoxyacetic Acid and 2,4-Dimethylamine Salt in Human Volunteers. J Toxicol Environ Health 36 (3) 233–240

    CAS  Google Scholar 

  63. Weber LW, Zesch A, Rozman K (1991): Penetration, Distribution and Kinetics of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Human Skinin vitro. Arch Toxicol 65, 421–428

    Article  CAS  Google Scholar 

  64. Andreas MG, McLachlan MS (2002): Modeling Digestive Tract Absorption and Desorption of Lipophilic Organic Contaminants in Humans. Environ Sci Technol 36, 3318–33325

    Article  CAS  Google Scholar 

  65. Kew GA, Schaum JL, White P, Evans TT (1989): Review of Plant Uptake of 2,3,7,8-TCDD from Soil and Potential Influences of Bio-availability. Chemosphere 18, 1313–1318

    Article  Google Scholar 

  66. Wipf HK, Hornberger E, Neuner N, Ranalder UB, Vetter W, Vuill-eumier PP (1981): TCDD-Levels in Soil and Plant Samples from Seveso Area. In: Hutzinger O, Frei RW, Merian E, Pocchiari F (eds), Chlorinated Dioxins and Related Compounds - Impact on the Environment. Pergamon Series on Environmental Science. Pergamon Press, Oxford. Vol 5: 105–114

    Google Scholar 

  67. Fries GF, Paustenbach DJ (1990): Evaluation of Potential Transmission of 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Contaminated Incinerator Emissions to Humans Via Foods. J Toxicol Environ Health 29, 1–43

    Article  CAS  Google Scholar 

  68. Newton M, Synder SP (1978): Exposure of Forest Herbivores to 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) in Areas Sprayed with 2,4,5-T. Bull Environ Contam Toxicol 20, 743–750

    Article  CAS  Google Scholar 

  69. Isensee AR, Jones GE (1975): Distribution of 2,3,7,8-Tetrachlorodi-benzo-p-dioxin (TCDD) in Aquatic Model Ecosystem. Environ Sci Technol 9, 668–672

    Article  CAS  Google Scholar 

  70. Giri BS, Karimi IA, Ray MB (2001): Modeling and Monte Carlo Simulation of TCDD Transport in a River. Water Res 35: 1263–1279

    Article  CAS  Google Scholar 

  71. Ruby MV, Fehling KA, Paustenbach DJ, Landenberger BD, Hols-apple MP (2002) Oral Bioaccessability of Dioxins/furans at Low Concentrations (50–350 ppt Toxicity Equivalent) in Soil. Environ Sci Technol 3 (22) 4905–11

    Article  CAS  Google Scholar 

  72. Andreas MG, McLachlan MS (2001): The Influence of Dietary Concentration on the Absorption and Excretion of Persistent Lipophilic Organic Pollutants in the Human Intestinal Tract. Chemosphere 45 (2) 201–211

    Article  Google Scholar 

  73. Young AL (2004): TCDD Biomonitoring and Exposure to Agent Orange: Still the Gold Standard. ESPR - Environ Sci & Pollut Res 11 (3) 143–146

    Article  CAS  Google Scholar 

  74. The Air Force Health Study - Final Report (2000): Chapter 2. Dioxin Assay. Prepared by SAIC for the Air Force Research Laboratory, Brooks AFB, TX

  75. Kang HK, Dalager NA, Needham LL, Patterson DG, Matanoski GM, Lees PS (2001): Health Status of US Army Chemical Corps Vietnam Era Veterans Relative to Current Dioxin Concentration. Organohalogen Compounds 54, 392–395

    Google Scholar 

  76. Centers for Disease Control (1988): Serum 2,3,7,8-Tetrachlorodi-benzo-p-dioxin in US Army Vietnam-era Veterans. JAMA 260 (9) 1249–1254

    Article  Google Scholar 

  77. Centers for Disease Control (1988): Health Status of Vietnam Veterans: II. Physical Health. JAMA 259, 2708–2714

    Article  Google Scholar 

  78. Centers for Disease Control (1990): The Association of Selected Cancers with Service in the US Military in Vietnam: Final Report, US Department of Health and Human Services, Atlanta GA

    Google Scholar 

  79. Centers for Disease Control (1990): The Association of Selected Cancers with Service in the US Military in Vietnam: I. Non-Hodgkin’s Lymphoma. Arch Int Med 150, 2473–2483

    Article  Google Scholar 

  80. Centers for Disease Control (1987): Postservice Mortality Among Vietnam Veterans. JAMA 257, 790–795

    Article  Google Scholar 

  81. Centers for Disease Control (1988): Health Status of Vietnam Veterans. I. Psychosocial Characteristics. JAMA 259, 2701–1707

    Article  Google Scholar 

  82. Michalek JE, Akhtar FZ, Ketchum NS, Jackson WG (2001): The Air Force Health Study: A Summary of Results. Organohalogen Compounds 54, 396–399

    Google Scholar 

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Authors and Affiliations

  1. Institute for Science and Public Policy, The University of Oklahoma, Norman, Oklahoma, USA

    Alvin L. Young

  2. Department of Zoology, National Food Safety and Toxicology Center, and Center for Integrative Toxicology, Michigan State University, East Lansing, Michigan, USA

    John P. Giesy & Paul D. Jones

  3. Department of Forest Science, Oregon State University, Corvallis, Oregon, USA

    Michael Newton

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Young, A.L., Giesy, J.P., Jones, P.D. et al. Environmental fate and bioavailability of agent orange and its associated dioxin during the vietnam war. Environ Sci & Pollut Res 11, 359–370 (2004). https://doi.org/10.1007/BF02979652

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