Abstract
The EtOAc andn-BuOH soluble fractions from the aerial part ofSetaria viridis showed a strong free radical scavenging activity. Six major compounds were isolated from these fractions. They were identified by spectral data as tricin (1),p-hydroxycinnamic acid (2), vitexin 2″-O-xyloside (3), orientin 2″-O-xyloside (4), tricin-7-O-β-D-glucoside (5) and vitexin 2″-O-glucoside (6). Among these compounds,4 and5 exhibited strong free radical scavenging activities on 1, 1-diphenyl-2-picrylhydrazyl (DPPH). We further studied the effects of these isolated compounds on the lipid peroxidation in rat liver microsomes induced by non-enzymatic method. As expected,4 and5 exhibited significant inhibition on ascorbic/Fe2- induced lipid peroxidation in rat liver microsomes.
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Kwon, Y.S., Kim, E.Y., Kim, W.J. et al. Antioxidant constituents fromSetaria viridis . Arch Pharm Res 25, 300–305 (2002). https://doi.org/10.1007/BF02976630
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DOI: https://doi.org/10.1007/BF02976630