Abstract
The genome sequencing project has generated and will continue to generate enormous amounts of sequence data. Since the first complete genome sequence of bacteriumHacmophilus influenzac was published in 1995, the complete genome sequences of 2 eukaryotic and about 22 prokaryotic organisms have been determined. Given this ever-increasing amounts of sequence information, new strategies are necessary to efficiently pursue the next phase of the genome project—the elucidation of gene expression patterns and gene product function on a whole genome scale. In order to assign functional information to the genome sequence, DNA chip technology was developed to efficiently identify the differential expression pattern of independent biological samples. DNA chip provides a new tool for genome expression analysis that may revolutionize many aspects of human life including new drug discovery and human disease diagnostics.
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Hwang, S.Y., Lim, G. DNA Chip technologies. Biotechnol. Bioprocess Eng. 5, 159–163 (2000). https://doi.org/10.1007/BF02936587
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DOI: https://doi.org/10.1007/BF02936587