Journal of Genetics

, Volume 74, Issue 1, pp 19-24

First online:

A compact proof of Fisher’s Fundamental Theorem for multiple loci

  • Narayan BeheraAffiliated withDevelopmental Biology and Genetics Laboratory, Indian Institute of Science

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A systematic method is formulated to carry out theoretical analysis in a multilocus multiallele genetic system. As a special application, the Fundamental Theorem of Natural Selection is proved (in the continuous time model) for a multilocus multiallele system if all pairwise linkage disequilibria are zero.


Evolution natural selection allele frequency variance in fitness integral variational principle