Abstract
Selenium was added to the feed of White Leghorn type chickens 1 day prior to challenge with eitherEscherichia coli or sheep erythrocyte antigen. the incidence of death or lesions was reduced from 86% to 21% at the optimal dose of selenium (0.4 mg/kg resulting in feed concentration of 0.45 mg/kg). After the chickens were stressed by chilling, selenium was ineffective againstE. coli. Dietary additions of selenium between 0.1 and 0.8 mg/kg resulted in an antibody titer increase from 2.2 to 3.9 to the log2 against sheep erythrocytes (SRBC). Followng chilling, antibody titer response was reduced from 4.9 to 2.4 to the log2. This titer reduction could be prevented with dietary additions of selenium between 0.1 and 1.2 mg/kg. The effects of a nitrofuran and selenium were additive againstE. coli challenge infection.
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Larsen, C.T., Pierson, F.W. & Gross, W.B. Effect of dietary selenium on the response of stressed and unstressed chickens toEscherichia coli challenge and antigen. Biol Trace Elem Res 58, 169–176 (1997). https://doi.org/10.1007/BF02917469
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DOI: https://doi.org/10.1007/BF02917469