General Article


, Volume 10, Issue 3, pp 28-34

First online:

“That which we call a rose by any other name would smell as sweet”: How the nose knows!

Nobel Prize in Physiology or Medicine 2004
  • Sayanti Saha
  • , Parvathy Ramakrishnan
  • , Sandhya S VisweswariahAffiliated withDepartment of Molecular Reproduction, Development and Genetics Indian Institute of Science Email author 

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Richard Axel and Linda B Buck received the Nobel Prize for their discoveries leading to an understanding of how odors are perceived. A large family of receptors present in the nasal epithelium are activated by specific odorants and relay information on the signal to the brain, allowing us to have the sense of smell.


Odorant receptor G-protein coupled receptors signal transduction