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Granular cell tumor of the ascending colon: A case report

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Summary

A granular cell tumor (granular cell myoblastoma) of the ascending colon in a 48-year old male is reported. The tumor was detected by barium enema study as a sessile polyp, and colonofiberscopy revealed submucosal tumor. It was removed by endoscopic polypectomy. Macroscopic examination showed the characteristic features of granular cell tumor. The avidin-biotin-peroxidase complex (ABC) method for detection of S-100 protein demonstrated that the cytoplasm of tumor cells and the pleomorphic nuclei were strongly stained with anti-S-100 protein serum, which supports the concept of the Schwann cell origin of granular cell tumor.

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Authors and Affiliations

  1. The Fourth Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya-shi, 663, Hyogo, Japan

    Akihiko Kawaura M.D., Shinobu Nishikawa M.D., Noritoshi Tanida M.D., Kazutami Tamura M.D., Tadatsugu Ohno M.D., Isao Ohama M.D., Masakatsu Kano M.D. & Takashi Shimoyama M.D.

  2. First Department of Pathology, Tokushima University School of Medicine, 770, Tokushima, Japan

    Toshiaki Sano M.D.

Authors
  1. Akihiko Kawaura M.D.
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  2. Shinobu Nishikawa M.D.
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  3. Noritoshi Tanida M.D.
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  4. Kazutami Tamura M.D.
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  5. Tadatsugu Ohno M.D.
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  6. Isao Ohama M.D.
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  7. Masakatsu Kano M.D.
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  8. Takashi Shimoyama M.D.
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  9. Toshiaki Sano M.D.
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Kawaura, A., Nishikawa, S., Tanida, N. et al. Granular cell tumor of the ascending colon: A case report. Gastroenterol Jpn 22, 88–91 (1987). https://doi.org/10.1007/BF02806339

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  • DOI: https://doi.org/10.1007/BF02806339

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