Notas Clínicas

Revista de Oncología

, Volume 6, Issue 9, pp 541-543

Diabetes insípida central como primera manifestación clínica de un carcinoma colorrectal metastásico

  • Mónica Corral SubíasAffiliated withServicio de Oncología Médica, Hospital de Alcañiz Email author 
  • , Vicente Alonso OrduñaAffiliated withServicio de Oncología Médica, Hospital Universitario Miguel Servet
  • , Rosana Grández Ladrón de GuevaraAffiliated withServicio de Oncología Médica, Hospital Universitario Miguel Servet
  • , Abigail Ruiz de Lobera MartínezAffiliated withServicio de Oncología Médica, Hospital Universitario Miguel Servet
  • , Teresa Puértolas HernándezAffiliated withServicio de Oncología Médica, Hospital Universitario Miguel Servet
  • , Antonio Antón TorresAffiliated withServicio de Oncología Médica, Hospital Universitario Miguel Servet

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Palabras clave

diabetes insípida metástasis glándula pituitaria

Diabetes insipidus as first manifestation of metastatic colorectal cancer

Abstract

Metastases of systemic tumours in the hypothalamus-pituitary region are reported to be around 1% to 4% of all intra-cranial metastases. Most of them are diagnosed when the primary tumour is operated-upon, or when widespread metastases occur. The metastasic infiltration of this region is usually asymptomatic and rarely recognised ante-mortem. The metastases rarely clinically manifest, but diabetes insipidus is the most frequent. Autopsy studies have shown breast and lung cancer are the mostfrequent cause of the metastases in this region.

We present a clinical case of a patient presenting diabetes insipidus as the first manifestation of a metastasic colorectal cancer.

Key words

diabetes insipidus metastases pituitary gland