Article

Journal of Chemical Sciences

, Volume 114, Issue 3, pp 197-201

Synthesis of novel cationic lipids with fully or partially non-scissile linkages between the hydrocarbon chains and pseudoglyceryl backbone

  • Santanu BhattacharyaAffiliated withDepartment of Organic Chemistry, Indian Institute of Science
  • , Saubhik HaldarAffiliated withDepartment of Organic Chemistry, Indian Institute of Science

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Abstract

Five novel cationic lipids with fully or partiallynon-scissile linkage regions between the pseudoglyceryl backbone and the hydrocarbon chains have been synthesized. The membrane-forming properties of these new lipids are briefly presented.

Keywords

Cationic lipids non-scissile linkages glycerol backbone membranes gene transfection