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On a model and the kinetics of photo-enhanced enzyme reactions

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Abstract

The recently observed enhancement, by laser irradiation, of the specific activity of the enzyme chymotrypsin (which hydrolyses Benzoyl-L-tyrosine-ethyl ester) at low enzyme concentration is considered. The enhancement of the reaction rate is attributed to a coherently excited state of the enzyme molecule (activated through Raman scattering of the laser light) following a prediction due to Fröhlich. The model is described, the kinetics of the process is framed and the observed enzyme-concentration dependence of the specific activity is reproduced.

Predictions of the model are delineated to urge verification of the main contentions through further experimentation.

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Authors and Affiliations

  1. Bose Institute, 700009, Calcutta, India

    Debajyoti Bhaumik

  2. Birla Institute of Technology and Science, Pilani, Rajastan, India

    Kamales Bhaumik

  3. Physics Department, Viswa Bharati, Santiniketan, India

    Asim Kumar Ray

  4. Saha Institute of Nuclear Physics, Calcutta-9, India

    Binayak Dutta-Roy

Authors
  1. Debajyoti Bhaumik
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  2. Kamales Bhaumik
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  3. Asim Kumar Ray
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  4. Binayak Dutta-Roy
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Bhaumik, D., Bhaumik, K., Ray, A.K. et al. On a model and the kinetics of photo-enhanced enzyme reactions. Bltn Mathcal Biology 40, 719–726 (1978). https://doi.org/10.1007/BF02460602

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  • DOI: https://doi.org/10.1007/BF02460602

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