Abstract
The effects of epinephrine, β-adrenergic agonist terbutaline sulfate, and cAMP phosphodiesterase inhibitor theophylline on proliferative response of peripheral blood lymphocytes from healthy subjects were studied in cultures with phytohemagglutinin and concanavalin A. Both adrenergic agonists inhibited lymphocyte blastogenesis, but the effect of epinephrine was more pronounced.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Yu. N. Tyurin and A. A. Makarov,Computer Processing of Data [in Russian], Moscow (1995).
A. A. Yarilin,Cell Factors of Immunogenesis Regulation [in Russian], Novosibirsk (1985), pp. 24–39.
A. DelRey, H. O. Besedovsky, E. Sorkin, et al.,Cell Immunol.,63, No. 2, 329–334 (1981).
J. U. Jetschmann, R. J. Benschop, R. Jacobs, et al.,J. Neuroimmunol.,74, No. 1-2, 159–164 (1997).
B. Kurz, J. Feindt, B. VonGaudecker, et al.,Brit. J. Pharmacol.,120, No. 8, 1401–1408 (1997).
M. Plaut,Annu. Rev. Immunol.,5, 621–669 (1987).
V. M. Sanders,Adv. Neuroimmunol.,5, No. 3, 283–298 (1995).
M. Schedlowski, W. Hosch, R. Oberbeck, et al.,J. Immunol.,156, No. 1, 93–99 (1996).
R. N. Spengler, S. W. Chensue, D. A. Giacherio, et al.,—Ibid.,152, No. 6, 3024–3031 (1994).
A. D. Strosberg,Obes. Res.,3, Suppl. 4, 501–505 (1995).
Author information
Authors and Affiliations
Additional information
Translated fromByulleten' Eksperimental' noi Biologii i Meditsiny, Vol. 128, No. 8, pp. 207–209, August, 1999
Rights and permissions
About this article
Cite this article
Shilov, Y.I., Gein, S.V. Adrenergic regulation of lymphocyte proliferative response in cultures with T-cell mitogens. Bull Exp Biol Med 128, 839–842 (1999). https://doi.org/10.1007/BF02433829
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02433829