, Volume 7, Issue 7, pp 261–262

Sur l'existence, dans la molécule des acides nucléiques, d'une structure secondaire à liaisons labiles

  • R. Thomas
Kurze Mitteilungen

DOI: 10.1007/BF02154543

Cite this article as:
Thomas, R. Experientia (1951) 7: 261. doi:10.1007/BF02154543


The existence of labile bonds participating in the macromolecular structure and the biological activity of nucleic acids is suggested. Mild conditions (pH 3·2 or heating to 38°C) induce an increase in molecular extinction which might be due to the destruction of such bonds. The critical temperatures are of the same order as those inducing thermal shock responsible for inhibition of embryonic morphogenesis.

Copyright information

© Birkhäuser Verlag 1951

Authors and Affiliations

  • R. Thomas
    • 1
  1. 1.Laboratoire de morphologie animaleUniversité libre de BruxellesBelgium