Kurze Mitteilungen


, Volume 7, Issue 7, pp 261-262

First online:

Sur l'existence, dans la molécule des acides nucléiques, d'une structure secondaire à liaisons labiles

  • R. ThomasAffiliated withLaboratoire de morphologie animale, Université libre de Bruxelles

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access


The existence of labile bonds participating in the macromolecular structure and the biological activity of nucleic acids is suggested. Mild conditions (pH 3·2 or heating to 38°C) induce an increase in molecular extinction which might be due to the destruction of such bonds. The critical temperatures are of the same order as those inducing thermal shock responsible for inhibition of embryonic morphogenesis.