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Cytogenetic characterization of congenital or infantile fibrosarcoma

  • Medical Genetics
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Abstract

Chromosome analysis of a congenital or infantile fibrosarcoma from the lower left leg of a 3-week-old baby girl showed only numerical changes involving chromosomes 11, 17 and 20. As three more cases with similar combinations of trisomies of the same chromosomes have been described, this report confirms that adult and congenital fibrosarcoma are cytogenetically different and trisomy 11 may be the key-event.

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Authors and Affiliations

  1. Centre for Human Genetics, University of Leuven, Herestraat 49, B-3000, Belgium

    P. Dal Cin & H. Van den Berghe

  2. Department of Paediatrics, University of Leuven, Herestraat 49, B-3000, Belgium

    P. Brock & M. Casteels-Van Daele

  3. Department of Oncological Surgery, University of Leuven, Herestraat 49, B-3000, Belgium

    I. De Wever

  4. Department of Pathology, University of Leuven, Herestraat 49, B-3000, Belgium

    B. Van Damme

Authors
  1. P. Dal Cin
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  2. P. Brock
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  3. M. Casteels-Van Daele
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  4. I. De Wever
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  5. B. Van Damme
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  6. H. Van den Berghe
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Dal Cin, P., Brock, P., Casteels-Van Daele, M. et al. Cytogenetic characterization of congenital or infantile fibrosarcoma. Eur J Pediatr 150, 579–581 (1991). https://doi.org/10.1007/BF02072211

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  • DOI: https://doi.org/10.1007/BF02072211

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