Summary
In this study the effects of the dietary fat sources, viz., Dalda, mustard oil and groundnut oil in the brain lipid metabolism during starvation has been investigated. To find out this, these oils were fed to albino rats for 8 weeks followed by 3 and 5 days of starvation. Total as well as galactolipids of brain were not affected by dietary oils and starvation, whereas phospholipids of brain were significantly increased by fasting irrespective of the dietary fats. On the other hand, cholesterol was found to be increased in the groups fed with Dalda and groundnut oil and to be significantly decreased during fasting experiments.
Incorporation of (1-14C)acetate into lipid of the brain slices of rats fed different experimental diets than followed by starvation revealed that the uptake of radioactivity was higher in the group fed with groundnut oil, followed by Dalda. Low uptake was observed in the group fed with mustard oil.
Zusammenfassung
Der Einfluß verschiedener Nahrungsfette auf den Lipidstoffwechsel des Gehirns während Hunger wurde untersucht. Albinoratten wurden 8 Tage lang mit Dalda, Senföl oder Erdnußöl gefüttert. Einige Tiere blieben anschließend 3 und 5 Tage lang ohne Nahrung. Die Gesamtlipide und die Galaktolipide wurden durch Nahrungsfette und durch Hunger nicht beeinflußt, während die Phospholipide unabhängig von der Art des Nahrungsfetts signifikant zunahmen. Cholesterin nahm in den mit Dalda und mit Erdnußöl gefütterten Gruppen zu und nahm ab während des Hungerns. In der Hungerperiode im Anschluß an die Fettzufuhr war der Einbau von 1-14C-Acetat in Lipide von Gehirnschnitten nach Erdnußöl höher als nach Dalda. Nach Senföl war der Einbau nur gering.
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Singh, S., Gupta, N. Effects of various oils and of starvation on the lipid metabolism in brain. Z Ernährungswiss 23, 276–282 (1984). https://doi.org/10.1007/BF02020640
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DOI: https://doi.org/10.1007/BF02020640