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Effects of various oils and of starvation on the lipid metabolism in brain

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Summary

In this study the effects of the dietary fat sources, viz., Dalda, mustard oil and groundnut oil in the brain lipid metabolism during starvation has been investigated. To find out this, these oils were fed to albino rats for 8 weeks followed by 3 and 5 days of starvation. Total as well as galactolipids of brain were not affected by dietary oils and starvation, whereas phospholipids of brain were significantly increased by fasting irrespective of the dietary fats. On the other hand, cholesterol was found to be increased in the groups fed with Dalda and groundnut oil and to be significantly decreased during fasting experiments.

Incorporation of (1-14C)acetate into lipid of the brain slices of rats fed different experimental diets than followed by starvation revealed that the uptake of radioactivity was higher in the group fed with groundnut oil, followed by Dalda. Low uptake was observed in the group fed with mustard oil.

Zusammenfassung

Der Einfluß verschiedener Nahrungsfette auf den Lipidstoffwechsel des Gehirns während Hunger wurde untersucht. Albinoratten wurden 8 Tage lang mit Dalda, Senföl oder Erdnußöl gefüttert. Einige Tiere blieben anschließend 3 und 5 Tage lang ohne Nahrung. Die Gesamtlipide und die Galaktolipide wurden durch Nahrungsfette und durch Hunger nicht beeinflußt, während die Phospholipide unabhängig von der Art des Nahrungsfetts signifikant zunahmen. Cholesterin nahm in den mit Dalda und mit Erdnußöl gefütterten Gruppen zu und nahm ab während des Hungerns. In der Hungerperiode im Anschluß an die Fettzufuhr war der Einbau von 1-14C-Acetat in Lipide von Gehirnschnitten nach Erdnußöl höher als nach Dalda. Nach Senföl war der Einbau nur gering.

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References

  1. Smith ME (1963) The effect of fasting on lipid metabolism of central nervous system of the rat. J Neurochem 10:531

    Article  CAS  Google Scholar 

  2. Leveille GA (1969)In vivo fatty acid and cholesterol synthesis in fasted and fasted-refed chicks. J Nutr 98:367.

    CAS  Google Scholar 

  3. Hiroo-Suzuki, Goshi A, Sugisawa H (1975) Effect of previous feeding of a high carbohydrate and high fat diet on changes in body weight and body composition of fasted rats. J Nutr 105:90

    Google Scholar 

  4. Brian LG, Morgan JO, Winick M (1981) Effect of essential fatty acid deficiency during late and behaviour in the progeny. Brt J Nutr 46:223

    Article  Google Scholar 

  5. Reddy PV, Sastry PS (1978) Effect of undernutrition on the metabolism of phospholipids and gangliosides in developing brain. Brt J Nutr 40:403

    Article  CAS  Google Scholar 

  6. Folch J, Lees M, Sloane-Stanley GH (1957) A simplified method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226:497

    CAS  Google Scholar 

  7. Ames BN (1966) Methods in Enzymology. In: Neufeld EF, Griusberg V (eds) Pub Academic Press, New York, Vol 8, p 115

    Google Scholar 

  8. Zlatkis A, Zak B (1969) Study of new cholesterol reagent. Anal Biochem 29:143

    Article  CAS  Google Scholar 

  9. Luddy FE, Barford RA, Herb SF, Paul M (1968) A rapid and quantitative procedure for the production of methyl esters of butter oil and other fats. J Am Clin Chem Soc 45:549

    CAS  Google Scholar 

  10. Bhattathiry EPM (1966) Influence of diets containing different natural oils on incorporation of (1-14C)acetate in the various fractions of rat liver. J Nutr 20:553

    Article  CAS  Google Scholar 

  11. Carreau JP, Thoron A, Capons D, Ranlin J (1968) Metabolism del'acide Erucique. I. Conversion of an acid oleique. Bull Soc Chim Biol 50:1973

    CAS  Google Scholar 

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Singh, S., Gupta, N. Effects of various oils and of starvation on the lipid metabolism in brain. Z Ernährungswiss 23, 276–282 (1984). https://doi.org/10.1007/BF02020640

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  • DOI: https://doi.org/10.1007/BF02020640

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