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Cranial chordomas in infancy and childhood. A report of two cases and review of the literature

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Abstract

Cranial chordomas are uncommon, accounting for less than 1% of all intracranial neoplasms. Although they are presumed to arise from congenital notochordal remnants, it is rare for these tumors to present in childhood. Only 35 cases of cranial chordomas have been reported in children 16 years of age or younger. We report 2 additional cases of pediatric cranial chordomas. One occurred in a 4 month old infant and to our knowledge represents the earliest age of presentation yet reported. The second case documents the value of MR imaging in delineating the extent of the tumor and defining its relationship to adjacent structures.

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References

  1. Horowitz T (1941) Chordal ectopic and its possible relation to chordomas. Arch Pathol Lab Med 31: 354

    Google Scholar 

  2. Pena CE, Horrat BL, Fisher ER (1970) The ultrastructure of chordoma. Am J Clin Pathol 53: 544

    PubMed  Google Scholar 

  3. Heffelfinger MJ, Dahlin DC, MacCarty CS, Beaubout JW (1973) Chordomas and cartilaginous tumors, at the skull base. Cancer 32: 410

    PubMed  Google Scholar 

  4. Bartel AD, Heilbronn YD (1970) Transcervical removal of a clivus chordoma in the 2 year old child. Reversal of quadriplegia and bulbar paralysis. Acta Neurochir (Wien) 23: 127

    Google Scholar 

  5. Utne JR, Pugh DG (1955) The roentgenologic aspects of chordoma. AJR 74: 593

    Google Scholar 

  6. Mabrey RE (1936) Chordoma: a study of 150 cases. Am J Cancer 25: 501

    Google Scholar 

  7. Wold LE, Laws ER (1983) Cranial chordomas in children and young adults. J Neurosurg 59: 1043

    PubMed  Google Scholar 

  8. Amendola BE, Amendola MA, Oliver E, McClatchey KD (1986) Chordoma: role of radiation therapy. Radiology 158: 839

    PubMed  Google Scholar 

  9. Becker LE, Yates AJ, Hoffman HJ, Norman MG (1975) Intracranial chordoma in infancy. Case report. J Neurosurg 42: 349

    PubMed  Google Scholar 

  10. Chambers PW, Schwinn CP (1978) Chordoma. A clinicologic study of metastasis. Am J Clin Pathol 72: 765

    Google Scholar 

  11. Congdon CC (1952) Benign and malignant chordomas. A clinocoanatomical study of twenty-two cases. Am J Pathol 28: 793

    PubMed  Google Scholar 

  12. Cummings BJ, Hodson DI, Bush RS (1983) Chordoma: the results of megavoltage radiation therapy. Int J Radiat Oncol Biol Phys 9: 633

    PubMed  Google Scholar 

  13. Eriksson B, Gunterberg B, Kindblom LG (1981) Chordoma: a clinicopathologic and prognostic study of a Swedish national series. Acta Orthop Scand 52: 49

    PubMed  Google Scholar 

  14. Gerlach J, Jensen HP, Koos W, Kraus H (1967) Pädiatrische Neurochirurgie. Stuttgart, Thieme

    Google Scholar 

  15. Higinbotham NL, Philipps RF, Farr HW, Hustin HD (1967) Chordoma—25 year study at Memorial Hospital. Cancer 20: 1841

    PubMed  Google Scholar 

  16. Kamrin RP, Potanus JN, Pool JL (1964) An evaluation of the diagnosis and treatment of chordoma. J Neurol Neurosurg Psychiatr 27: 157

    Google Scholar 

  17. Kendall BE, Lee BCP (1977) Cranial chordomas. Br J Radiol 50: 587

    PubMed  Google Scholar 

  18. Kerr WA, Allen KL, Haynes DR, et al. (1975) Familial nasopharyngeal chordoma (Letter). S Afr Med J 49: 1584

    PubMed  Google Scholar 

  19. Krayenbuhl H, Yasargil MG (1975) Cranial chordomas. Progr Neurol Surg 6: 380

    Google Scholar 

  20. Larson TC, Houser OW, Laws ER (1987) Imaging of cranial chordomas. Mayo Clin Proc 62: 886

    PubMed  Google Scholar 

  21. Meyer JE, Oot RF, Lindfors KK (1986) CT appearance of clival chordomas. J Comput Assist Tomogr 10: 34

    PubMed  Google Scholar 

  22. Mills RP (1984) Chordomas of the skull base. J R Soc Med 77: 10

    PubMed  Google Scholar 

  23. Montgomery AH, Wolman IJ (1933) Sacrococcygeal chordomas in children. Am J Dis Child 46: 1263

    Google Scholar 

  24. O'Neill P, Bell BA, Miller JD, Jacobson I, Guthrie W (1985) Fifty years of experience with chordomas in southeast Scotland. Neurosurgery 16: 166

    PubMed  Google Scholar 

  25. Plese JPP, Borges JM, Nudelman M, Lefevre AB, Sallum J (1978) Unusual subarachnoid metastasisof an intracranial chordoma in infancy. Childs Brain 4: 251

    PubMed  Google Scholar 

  26. Raffel C, Wright DC, Gutin PH, Wilson CB (1985) Cranial chordomas: clinical presentation and results of operative and radiation therapy in twenty-six patients. Neurosurgery 17: 703

    PubMed  Google Scholar 

  27. Rich TA, Schiller A, Suit HD, Mankin HJ (1985) Clinical and pathologic review of 48 cases of chordoma. Cancer 56: 182

    PubMed  Google Scholar 

  28. Richter HJ Jr, Batsakis JG, Boles R (1975) Chormomas: nasopharyngeal presentation and atypical long survival. Ann Otol Rhinol Laryngol 84: 327

    PubMed  Google Scholar 

  29. Rougerie J, Guiot G, Bouche J, Trigo JC (1967) Les voies d'abord des chordomes du clivus. Neurochirurgie 13: 559

    PubMed  Google Scholar 

  30. Sassin JF, Churorian AM (1967) Intracranial chordoma in children. Arch Neurol 17: 89

    PubMed  Google Scholar 

  31. Schneegans E, Mandigas M (1938) Hydrocephalie non communicante due a un chordome malin. Bull Soc Pediatr (Paris) 36: 535

    Google Scholar 

  32. Schroeder BA, Wells RG, Starshak RJ, Sty JR (1987) Clivus chordoma in a child with tuberous sclerosis: CT and MR demonstration. J Comput Assist Tomogr 11: 195

    PubMed  Google Scholar 

  33. Sze G, Uichanco LS, Brant-Zawadzki MN, Davis RL, Gutin PH, Wilson CB, Normal D, Newton TH (1988) Chordomas: MR imaging. Radiology 166: 187

    PubMed  Google Scholar 

  34. Wood EH, Himadi GM (1950) Chordomas: a roentgenologic study of 16 cases previously unreported. Radiology 54: 706

    PubMed  Google Scholar 

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Author notes

  1. R. B. Towbin

    Present address: Department of Radiology, Children's Hospital of Michigan, 3901 Beaubien Blvd., 48201, Detroit, MI, USA

Authors and Affiliations

  1. Department of Radiology and Pediatrics, Children's Hospital Medical Center, Elland & Bethesda Aves, 45229-2899, Cincinnati, Ohio, USA

    J. Matsumoto, R. B. Towbin & W. S. Ball Jr. M.D.

  2. Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA

    J. Matsumoto, R. B. Towbin & W. S. Ball Jr. M.D.

Authors
  1. J. Matsumoto
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  2. R. B. Towbin
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  3. W. S. Ball Jr. M.D.
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Matsumoto, J., Towbin, R.B. & Ball, W.S. Cranial chordomas in infancy and childhood. A report of two cases and review of the literature. Pediatr Radiol 20, 28–32 (1989). https://doi.org/10.1007/BF02010629

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  • DOI: https://doi.org/10.1007/BF02010629

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