Experientia

, Volume 35, Issue 6, pp 759–762

Hageman factor activation and tight junction disruption in mice challenged with attenuated endotoxin

  • R. I. Walker
  • M. Porvaznik
  • June E. Egan
  • A. M. Miller
Article

DOI: 10.1007/BF01968230

Cite this article as:
Walker, R.I., Porvaznik, M., Egan, J.E. et al. Experientia (1979) 35: 759. doi:10.1007/BF01968230

Summary

Endotoxin treated with chromium chloride is less toxic to mice than the parent molecule, but can disrupt intestinal permeability barriers and has an enhanced ability to activate Hageman factor.

Copyright information

© Birkhäuser Verlag 1979

Authors and Affiliations

  • R. I. Walker
    • 1
    • 2
  • M. Porvaznik
    • 1
    • 2
  • June E. Egan
    • 1
    • 2
  • A. M. Miller
    • 1
    • 2
  1. 1.Experimental Hematology DepartmentArmed Forces Radiobiology Research InstituteBethesdaUSA
  2. 2.Veterinary Medicine DepartmentArmed Forces Radiobiology Research InstituteBethesdaUSA