Experientia

, Volume 39, Issue 5, pp 514–518

Disruption of the goblet cell intercellular junction following histamine infusion of the rabbit ileum

Authors

  • M. Porvaznik
    • Experimental Hematology DepartmentArmed Forces Radiobilogy Research Institute
  • W. Baker
    • Experimental Hematology DepartmentArmed Forces Radiobilogy Research Institute
  • R. I. Walker
    • Experimental Hematology DepartmentArmed Forces Radiobilogy Research Institute
Article

DOI: 10.1007/BF01965183

Cite this article as:
Porvaznik, M., Baker, W. & Walker, R.I. Experientia (1983) 39: 514. doi:10.1007/BF01965183

Summary

Histamine infused into the mesenteric artery of the rabbit ileum ruptured tight junctional complexes linking goblet cells with neighboring absorptive epithelial or other goblet cells. Loss of tight junctional integrity induced by histamine could contribute to extra-intestinal endotoxemia reported after a variety of injuries.

Download to read the full article text

Copyright information

© Birkhäuser Verlag 1983