, Volume 43, Issue 9, pp 998–1002

Dynamics of excretion of urinary chemosignals in the house mouse (Mus musclus) during the natural estrous cycle


  • F. Andreolini
    • Department of ChemistryIndiana University
  • B. Jemiolo
    • Department of ChemistryIndiana University
  • M. Novotny
    • Department of ChemistryIndiana University
Full Papers

DOI: 10.1007/BF01952217

Cite this article as:
Andreolini, F., Jemiolo, B. & Novotny, M. Experientia (1987) 43: 998. doi:10.1007/BF01952217


The volatile fraction of urinary metabolites was investigated chromatographically at five different stages of the natural estrous cycle. A very substantial endocrine dependency has been noted for 11 compounds: 4 ketones, 2 acetate esters, 3 dihydrofuran isomers, dehydro-exo-brevicomin, and 2,5-dimethylpyrazine. The compounds were structurally verified through combined gas chromatography/mass spectrometry.

Key words

Estrous cyclefemale mouse urineurinary volatilescapillary gas chromatography/mass spectrometry

Copyright information

© Birkhäuser Verlag 1987