, Volume 32, Issue 2, pp 179-181

Adenyl cyclase activity of mouse liver membranes after incubation with endotoxin and epinephrine

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Adenyl cyclase activity in isolated mouse liver cell membranes was stimulated two-fold by endotoxin. Furthermore, endotoxin inhibited epinephrine induction of adenyl cyclase activity, apparently through interruption of the phospholipid moiety of the enzyme complex.