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Biology of the mast cell and its role in cutaneous inflammation

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References

  1. Atkins P C, Norman M E, Zweimann B (1978) Antigen induced neutrophil chemotactic activity in man. Correlation with bronchospasm and inhibition by disodium cromolgycate. J Allergy Clin Immunol 62: 149

    PubMed  Google Scholar 

  2. Bach M K, Brashler JR, Gorman RR (1977) On the structure of slow reacting substance of anaphylaxis: evidence of biosynthesis from arachidonic acid. Prostaglandins 14: 21

    PubMed  Google Scholar 

  3. Black J W, Duncan WAM, Durant CJ, Ganellin CR, Parsons EM (1972) Definition and antagonism of histamine H2-receptors. Nature 236: 385

    PubMed  Google Scholar 

  4. Bloom G D (1974) Structural and biochemical characteristics of mast cells. In: Zweifach BW, Grant L, McCluskey RT (eds) The inflammatory process. Academic Press, New York, P 545

    Google Scholar 

  5. Boswell R N, Austen KF, Goetzl EJ (1978). Intermediate molecular weight eosinophil chemotactic factors in rat peritoneal mast cells: immunological release, granule association, and demonstration of structural heterogeneity. J Immunol 120: 15

    PubMed  Google Scholar 

  6. Brocklehurst W E (1960) The release of histamine and formation of a slow-reacting substance (SRS-A) during anaphyactic shock. J Physiol 151: 416

    PubMed  Google Scholar 

  7. Caulfield JP, Lewis RA, Hein A, Austen KF (1980) Secretion in dissociated human pulmonary mast cells. J Cell Biol 85: 299

    PubMed  Google Scholar 

  8. Clark R A F, Gallin JI, Kaplan AP (1975) The selective eosinophil chemotactic activity of histamine. J Exp Med 142: 1462

    PubMed  Google Scholar 

  9. Clark R A F, Sandler JA, Gallin JI, Kaplan AP (1977) Histamine modulation of eosinophil migration. J Immunol 118: 137

    PubMed  Google Scholar 

  10. Conrad D H, Bazin H, Sehon AH, Froese A (1975) Binding parameters of the interaction between rat IgE and rat mast cell receptors. J Immunol 114: 1688

    PubMed  Google Scholar 

  11. Demopoulos C A, Pinckard RN, Hanahan DJ (1979) Platelet activating factor: evedence for 1-0-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine as the active component (a new class of lipid chemical mediators). J Biol Chem 254: 9355

    PubMed  Google Scholar 

  12. Dousa T P, Code CF (1974) Effect of histamine and its methyl derivatives on cyclic AMP metabolism in gastric mucosa and its blockage by an H2 receptor antagonist. J Clin Invest 53: 334

    PubMed  Google Scholar 

  13. Drazen J M, Lewis RA, Wasserman SI, Orange RP, Austen KF (1979) Differential effects of a partially purified preparation of slow-reacting substance of anaphylaxis on guinea pig tracheal spirals and parenchymal strips. J Clin Invest 63: 1

    PubMed  Google Scholar 

  14. Fedorko M F, Hirsch JG (1965) Crystalloid structures in granules of guinea pig basophils and human mast cells. J Cell Biol 26: 973

    Google Scholar 

  15. Goetzl E J, Austen KF (1975) Purification and synthesis of eosinophilotactic tetrapeptides of human lung tissue: identification as eosinophil chemotactic factor of anaphylaxis. Proc Natl Acad Sci USA 72: 4123

    PubMed  Google Scholar 

  16. Goetzl E J, Gorman RR (1978) Chemotactic and chemokinetic stimulation of human eosinophil and neutrophil polymorphonuclear leukocytes by 12-L-hydroxy-5, 8, 10-heptadecatrioenic acid (HHT). J Immunol 120: 526

    PubMed  Google Scholar 

  17. Goetzl E J, Woods JM, Gorman RR (1977) Stimulation of human eosinophil and neutrophil polymorphonuclear leukocyte chemotaxis and rnadom migration by 12-L-hydroxy-5, 8, 10, 14-eicosatetraenoic acid. J Clin Invest 59: 179

    PubMed  Google Scholar 

  18. Gomori G (1953) Chloroacetyl esters as histochemical substrates. J Histochem Cytochem 1: 469

    PubMed  Google Scholar 

  19. Greaves M, Marks R, Robertson I (1977) Receptors for histamine in human skin blood vessels: a review. Br J Dermatol 97: 225

    PubMed  Google Scholar 

  20. Henson P M (1977) Activation of rabbit platelets by platelet-activating factor derived from IgEsensitized basophils: characteristics of the aggregation and its dissociation from secretion. J Clin Invest 60: 481

    PubMed  Google Scholar 

  21. Holgate S, Lewis RA, Austen KF (to be published). Cyclic AMP and the release reaction. Prog Immunol

  22. Jakschik B A, Falkenhein S, Parker CW (1977) Precursor role of arachidonic acid in releas of slow reacting substance from rat basophilic leukemia cells. Proc Natl Acad Sci USA 74: 4577

    PubMed  Google Scholar 

  23. Johnson A R, Hugli RE, Möller-Eberhard HJ (1975) Release of histamine from rat mast cells by the complement peptides C3a and C5a. Immunology 28: 1067

    PubMed  Google Scholar 

  24. Kaliner M, Orange RP, Austen KF (1972) Immunological release of histamine and slow reacting substance of anaphylaxis from human lung. IV. Enhancement by cholinergic and alpha-adrenergic stimulation. J Exp Med 136: 556

    PubMed  Google Scholar 

  25. Kay AB, Austen KF (1971) The IgE-mediated release of an eosinophil leukocyte chemotactic factor from human lung. J Immuol 107: 899

    Google Scholar 

  26. Kay AB, Stechschulte DJ, Austen KF (1971) An eosinophil leukocyte chemotactic factor of anaphylaxis. J Exp Med 133: 602

    PubMed  Google Scholar 

  27. Kiernan JA (1975) A pharmacological and histological investigation of the involvement of mast cells in cutaneous axon reflex vasodilatation. Q J Exp Physiol 60: 123

    Google Scholar 

  28. König W, Ishizaka K (1974) Specific binding of mouse IgE with rat mast cells. J Immunol 112:1642

    Google Scholar 

  29. Kravis TC, Henson PM (1977) Accumulation of platelets at sites of antigen-antibody-mediated injury: a possible role for IgE antibody and mast cells. J Immunol 118: 1569

    PubMed  Google Scholar 

  30. Lagunoff D (1972) Contributions of electron microscopy to the study of mast cells. J Invest Dermatol 58: 296

    PubMed  Google Scholar 

  31. Lagunoff D, Pritzl P, Mueller L (1970)N-Acetyl-β-glucosaminidase in rat mast cell granules. Exp Cell Res 61: 129

    PubMed  Google Scholar 

  32. Lewis RA, Austen KF, Drazen JM, Clark DA, Corey EJ to be published Slow reacting substance of anaphylaxis: identification of leukotrienes C-1 and D from human and rat sources. Proc Natl Acad Sci USA

  33. Loos M, Volanakis JE, Stroud RM (1976) Mode of interaction of different polyanions with the first (C1, CT), the second (C2) and the fourth (C4) component of complement-II. Effect of polyanions on the binding of C2 to EAC4b. Immunochemistry 13: 257

    PubMed  Google Scholar 

  34. Lynch SM, Austen KF, Wasserman SI (1978) Release of arylsulfatase A but not B from rat mast cells by noncytolytic secretory stimuli. J Immunol 121: 1394

    PubMed  Google Scholar 

  35. McNeill JH, Verma SC (1974) Blockade by burimamide of the effects of histamine and histamine analogs on cardiac contractility, phosphorylase activation and cyclic adenosine monophosphate. J Pharmacol Exp Ther 188: 180

    PubMed  Google Scholar 

  36. Majno G, Palade GE, Schoefl GI (1961) Studies on inflammation. II. The site of action of histamine and serotonin along the vascular tree: a topographic study. J Biophys Biochem Cytol 11: 607

    PubMed  Google Scholar 

  37. Metcalfe DD, Lewis RA, Silbert JE, Rosenberg RD, Wasserman SI, Austen KF (1978) Isolation, identification, and characterization of heparin from human lung. Fed Proc 37: 1776

    Google Scholar 

  38. Metcalfe DD, Soter NA, Wasserman SI, Austen KF (1980) Identification of sulfated mucopolysaccharides, including heparin, in the lesional skin of a patient with mastocytosis. J Invest Dermatol 74: 210

    PubMed  Google Scholar 

  39. Mikhail GR, Miller-Milinska A (1964) Mast cell population in human skin. J Invest Dermatol 43: 249

    PubMed  Google Scholar 

  40. Moriyasu S, Yamura T (1973) Electron microscopic studies of mast cell degranulation. Acta Derm Venereol (Stockh.) 53 (Suppl 73): 149

    Google Scholar 

  41. Morrison DG, Henson PM (1978) Release of mediators from mast cells and basophils induced by different stimuli. In: Bach MK (ed) Immediate hypersensitivity. Modern concepts and developments. Marcel Dekker, New York and Basel, p 431

    Google Scholar 

  42. Murphy RC, Hammarström S, Samuelson B (1979) Leukotriene C: a slow-reacting substance from murine mastocytoma cells. Proc Natl Acad Sci USA 76: 4275

    PubMed  Google Scholar 

  43. Nadel JA (1973) Neurophysiologic aspects of asthma. In: Austen KF, Lichtenstein LM (eds) Asthma: Physiology, immunopharmacology and treatment. Academic Press, New York, P 29

    Google Scholar 

  44. Orange RP, Austen KF (1969) Slow reacting substance of anaphylaxis. Adv Immunol 10: 105

    PubMed  Google Scholar 

  45. Padawer J (1978) The mast cell and immediate hypersensitivity. In: Bach MK (ed) Immediate hypersensitivity. Modern concepts and developments. Marcel Dekker, New York and Basel, p 431

    Google Scholar 

  46. Paterson NAM, Wasserman SI, Said JW, Austen KF (1976) Release of chemical mediators from partially purified human hing mast cells. J Immunol 117: 1356

    PubMed  Google Scholar 

  47. Pugh D, Walker PG (1961) Histochemical localization of β-glucuronidase andN-acetyl-β-glucosaminidase. J Histochem Cytochem 9: 105

    PubMed  Google Scholar 

  48. Rocha e Silva M, Bier O, Aronson M (1951) Histamine release by anaphylatoxin. Nature 168: 465

    Google Scholar 

  49. Schayer RW (1965) Histamine and circulatory homeostasis. Fed Proc 24: 1295

    PubMed  Google Scholar 

  50. Schwartz LB, Austen KF (1980) Enzymes of the mast cell granule. J Invest Dermatol 74: 349

    PubMed  Google Scholar 

  51. Seppä HEJ (1978) Rat skin main neutral protease: immunohistochemical localization. J Invest Dermatol 71: 311

    PubMed  Google Scholar 

  52. Soter N A (1980) High molecular weight neutrophil chemotactic factor: recognition, characterization, and role in the deactivation of neutrophilic leukocytes. J Invest Dermatol 74: 354

    PubMed  Google Scholar 

  53. Soter N A, Mihm MC JR, Dvorak HF, Austen KF (1978) Cutaneous necrotizing venulitis: a sequential analysis of the morphologic alterations occurring after mast cell degranulation in a patient with a unique syndrome. Clin Exp Immunol 32: 46

    PubMed  Google Scholar 

  54. Soter N A, Wasserman SI, Austen KF (1976) Cold urticaria: release into the circulation of histamine and eosinophil chemotactic factor of anaphylaxis during cold challenge. N Eugl J Med 294: 687

    Google Scholar 

  55. Soter N A, Wasserman SI, Austen KF, McFadden ER JR (1980) Mast cell mediator release and alteration in lung function in individuals with cholinergic urticaria. N Engl J Med 302: 604

    PubMed  Google Scholar 

  56. Soter N A, Wasserman SI, Pathak MA, Parrish JA, Austen KF (1979) Solar urticaria: release of mast cell mediators into the circulation after experimental challenge. J Invest Dermatol 72: 282

    Google Scholar 

  57. Tomita A, Patterson R, Suszko IM (1974) Respiratory mast cells and basophiloid cells. Int Arch Allergy Appl Immunol 47: 261

    PubMed  Google Scholar 

  58. Trotter C M, Orr TSC (1974) A fine structure study of some cellular components in allergic reactions. II. Mast cells in normal and atopic human skin. Clin Allergy 4: 421

    Google Scholar 

  59. Turnbull L W, Evans DP, Kay AB (1977) Human eosinophils, acidic tetrapeptides (ECF-A) and histamine: interactions in vitro and in vivo. Immunology 32: 57

    PubMed  Google Scholar 

  60. Valone F H, Goetzl EJ (1978) Immunologic release in the peritoneal cavity of lipid chemotactic and chemokinetic factors for polymorphonuclear leukocytes. J Immunol 120: 102

    PubMed  Google Scholar 

  61. Wasserman S I, Austen KF (1976) Arylsulfatase B of human lung: isolation, characterization, and interaction with slow-reacting substance of anaphylaxis. J Clin Invest 57: 738

    PubMed  Google Scholar 

  62. Wasserman S I, Austen KF (1977) Identification and characterization of arylsulfatase A and B of the rat basophil leukemia tumor. J Biol Chem 252: 7074

    PubMed  Google Scholar 

  63. Wasserman S I, Goetzl EJ, Austen KF (1975) Inactivation of slow reacting substance of anaphylaxis by human eosinophil arylsulfatase. J Immunol 114: 645

    PubMed  Google Scholar 

  64. Wasserman S I, Soter NA, Center DM, Austen KF (1977) Cold urticaria: recognition and characterization of a neutrophil chemotactic factor which appears in serum during experimental cold challenge. J Clin Invest 60: 189

    PubMed  Google Scholar 

  65. Wasserman S I, Soter NA, Poser J, Austen KF (1980) Eosinophil chemotactic factors in human disease; evidence of heterogeneity. Clin Res 28: 254A

    Google Scholar 

  66. Weiler J M, Yurt RW, Fearon DT, Austen KF (1978) Modulation of the formation of the amplification convertase of complement, C3b, Bb by native and commercial heparin. J Exp Med 147: 409

    PubMed  Google Scholar 

  67. Woodbury R G, Gruzenski GM, Lagunoff D (1978) Immunofluorescent localization of a serine protease in rat small intestine. Proc Natl Acad Sci USA 75: 2785

    PubMed  Google Scholar 

  68. Yurt R, Austen KF (1977) Preparative purification of the rat mast cell chymase: characterization and interaction with granule components. J Exp Med 146: 1405

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Dermatology, Harvard Medical School, 250 Longwood Avenue, 02115, Boston, MA, USA

    Bruce U. Wintroub & Nicholas A. Soter

  2. Immunodermatology Section of the Department of Rheumatology and Immunology and Division of Dermatology, Brigham and Women's Hospital, 250 Longwood Avenue, 02115, Boston, MA, USA

    Bruce U. Wintroub & Nicholas A. Soter

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  1. Bruce U. Wintroub
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  2. Nicholas A. Soter
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Wintroub, B.U., Soter, N.A. Biology of the mast cell and its role in cutaneous inflammation. Springer Semin Immunopathol 4, 55–63 (1981). https://doi.org/10.1007/BF01891885

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