Abstract
An animal chamber was constructed which made possible the exposure of small animals for long periods of time to uniform controlled atmospheres containing a given number of cluster ions.Monitoring of the microenvironment was made possible by the fabrication of a minaturized ion collector.Using these two developments mice were exposed to non-ionized or to positively ionized air containing either 2% or 4% CO2. Non-ionized 2% or 4% CO2 produced a fall in the blood level of 5-HT.Positively ionized 2% or 4% CO2 elicited a rise in 5-HT providing the ionic density was sufficiently great.
Zusammenfassung
Eine Kammer zur langfristigen Exponierung von kleinen Versuchstieren in einer kontrollierten Atmosphäre mit einer gegebenen Zahl Luftionen wird beschrieben. Die Ionen wurden mit einem Miniatur-Ionen-sammler gemessen. In der Kammer wurden Mäuse nicht-ionisierte und ionisierter Luft mit 2% und 4% CO2 exponiert. Nicht-ionisierterCO2 Zusatz von 2 und 4% führte zur Senkung des 5-Hydroxytryptamin (5-HT)-Spiegels im Blut, während positiv ionisierter CO2 Zusatz einen Anstieg des 5-HT im Blut bewirkte, wenn die Ionendichte genügend gross war.
Resume
On a construit une cellule dans laquelle on peut exposer de petits animaux durant de longues périodes à des atmosphères contrôlées, uniformes et contenant un nombre déterminé d'ions. Les ions ont été dénombrés au moyen d'un collecteur miniature. On a alors placé dans la dite cellule des souris qui furent exposées à de l'air ionisé et non-ionisé contenant 2 et 4% de CO2. L'adjonction de 2 et 4% de CO2 nonionisé à l'air a provoqué une baisse du taux de 5-HT dans le sang,alors que l'apport de CO2 ionisé positivement a provoqué une hausse du taux de 5-HT dans le sang pour autant que le nombre d'ions était suffisant.
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With the technical assistance of Eddie J. Reed and S.M. Lamprecht.
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Krueger, A.P., Andriese, P.C. & Kotaka, S. The effects of inhaling non-ionized or positively ionized air containing 2–4% CO2 on the blood levels of 5-hydroxytryptamine in mice. Int J Biometeorol 10, 17–28 (1966). https://doi.org/10.1007/BF01636117
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DOI: https://doi.org/10.1007/BF01636117