Article

Journal of Autism and Developmental Disorders

, Volume 11, Issue 2, pp 165-173

Implication of sex differences in the familial transmission of infantile autism

  • Luke TsaiAffiliated withDepartment of Psychiatry, University of Iowa College of Medicine
  • , Mark A. StewartAffiliated withDepartment of Psychiatry, University of Iowa College of Medicine
  • , Gerald AugustAffiliated withDepartment of Psychiatry, University of Iowa College of Medicine

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Abstract

There are studies suggesting possible hereditary influence in autism. Data on 102 autistic children, 78 boys and 24 girls, showed that there was a significantly greater proportion of autistic girls than boys with IQs less than 50 and with evidence of brain damage. The autistic girls also had a greater proportion of relatives affected with autism or cognitive-language deficit than did the boys. The implication of sex differences in the possible mode of familial transmission of autism is discussed.