Summary
Periodic movements in sleep (PMS) can cause severe sleep disturbances. We investigated the central dopamine D2 receptor density in patients with PMS with123I-IBZM and single photon emission tomography (SPET). In PMS there was a lower123I-IBZMbinding in the basal ganglia compared tothe control group. The results indicate a loss of central D2 receptors in PMS.
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Staedt, J., Stoppe, G., Kögler, A. et al. Dopamine D2 receptor alteration in patients with periodic movements in sleep (nocturnal myoclonus). J. Neural Transmission 93, 71–74 (1993). https://doi.org/10.1007/BF01244940
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DOI: https://doi.org/10.1007/BF01244940