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Evidence of oxygen limitation in a hollow fibre reactor with immobilized E. coli

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Summary

A hollow fibre reactor (HFR) has been used to immobilize a regulatory mutant ofE. coli to produce phenylalanine. Fermentation performance in the HFR using both air and pure oxygen shows evidence of significant oxygen limitation. In particular, levels of volatile fatty acids (VFA) produced served as an indication of oxygen limitation.

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Authors and Affiliations

  1. School of Chemical Engineering and Industrial Chemistry and School of Biotechnology, University of New South Wales, P O Box 1, 2033, Kensington, NSW, Australia

    S. L. Paterson, A. G. Fane, C. J. D. Fell & P. L. R. Rogers

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  1. S. L. Paterson
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  2. A. G. Fane
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  3. C. J. D. Fell
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  4. P. L. R. Rogers
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Paterson, S.L., Fane, A.G., Fell, C.J.D. et al. Evidence of oxygen limitation in a hollow fibre reactor with immobilized E. coli. Biotechnol Lett 8, 561–564 (1986). https://doi.org/10.1007/BF01028083

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  • DOI: https://doi.org/10.1007/BF01028083

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