Summary
Supplementation of the culture medium with 2-deoxystreptidine allowsStreptomyces griseus MIT-5, an idiotrophic mutant, to produce an antibiotic which we have called streptomutin A. Degradation studies on the antibiotic showed that the aminocyclitol moiety is different from streptidine. Streptomutin A also is distinct from streptomycin in having a much different ratio of biological to chemical activity.
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This paper is Contribution No. 2746 from the Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, U.S.A.
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Lemke, J.R., Demain, A.L. Preliminary studies on streptomutin A. European J. Appl Microbiol. 2, 91–94 (1976). https://doi.org/10.1007/BF00942351
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DOI: https://doi.org/10.1007/BF00942351